Results 201 to 210 of about 3,757,704 (310)

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Integration of single-cell sequencing and transcriptomic analysis to identify novel diagnostic biomarkers for pre-eclampsia. [PDF]

open access: yesBMC Pregnancy Childbirth
Huang Z   +9 more
europepmc   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

open access: yesCancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

BMI-Dependent Associations of the Estradiol-Linked Polymorphism rs117585797 of the <i>Anoctamin-2</i> Gene with Pre-Eclampsia. [PDF]

open access: yesLife (Basel)
Churnosova M   +9 more
europepmc   +1 more source

Socioeconomic status, environmental factors, and motor function in children with cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To investigate the association between socioeconomic status and cerebral palsy (CP) motor function, adjusting for known clinical and candidate environmental risk factors, that is, air pollution and distance to a children's treatment center (CTC).
Hana F Alazem   +14 more
wiley   +1 more source

Perinatal complications, mode of delivery, and neurological morbidity in children with COL4A1/A2 variants

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To characterize reported perinatal complications and childhood neurological diagnoses among children with COL4A1/2 variants and explore associations between mode of delivery and selected neurological outcomes. Method This was a retrospective cross‐sectional patient registry study using surveys collected through the Gould Syndrome ...
Shraddha Pandey   +3 more
wiley   +1 more source

Prenatal exposure to paracetamol and the risk of autism and attention‐deficit/hyperactivity disorder: An umbrella review and meta‐meta‐analysis

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This meta‐meta‐analysis synthesizes evidence on prenatal paracetamol exposure and neurodevelopmental outcomes. Crude analyses suggest small associations with autism and ADHD, but these attenuate substantially when restricting to high‐quality meta‐analyses and low‐bias primary studies.
Hoda Tayebi‐Hillali   +5 more
wiley   +1 more source

Aspirin use for pre-eclampsia prevention in IVF/ICSI pregnancies in Kumasi, Ghana: a prospective cohort study. [PDF]

open access: yesReprod Health
Agana EA   +9 more
europepmc   +1 more source

Motor difficulties, motor‐related health care, and associating factors in children born extremely preterm

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Significant motor difficulties in children born extremely preterm were common and appear insufficiently managed. Factors associated with receiving motor‐related health care suggest care is driven more by comorbidities than motor need. Our findings reveal a care gap and underscore the need for extended follow‐up and management of non‐CP motor ...
Daniela Nosko   +4 more
wiley   +1 more source

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