In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia [PDF]
Antihypertensive drugs lower the maternal blood pressure in pre-eclampsia (PE) by direct or central vasodilatory mechanisms but little is known about the direct effects of these drugs on placental ...
Muttukrishna, S +8 more
core +2 more sources
Background The proportion of hyperglycosylated human chorionic gonadotropin (hCG-h) to total human chorionic gonadotropin (%hCG-h) during the first trimester is a promising biomarker for prediction of early-onset pre-eclampsia.
Katja Murtoniemi +11 more
doaj +1 more source
Management of pre-eclampsia [PDF]
Pre-eclampsia is part of a spectrum of conditions known as the hypertensive disorders of pregnancy (box 1).1 A multisystem disorder usually associated with raised blood pressure and proteinuria, pre-eclampsia is relatively common, affecting 2-8% of pregnancies.
Lelia, Duley +2 more
openaire +2 more sources
Preterm and term pre-eclampsia: relative burdens of maternal and perinatal complications. [PDF]
To determine the relative burdens of maternal and perinatal complications, for preterm and term pre-eclampsia. Prospective observational cohort study. Two English maternity units.
Akolekar, R. +4 more
core +1 more source
Obstetric management of severe pre eclampsia - eclampsia remote from term [PDF]
The Obstetric management of severe pre eclampsia - eclampsia at 32 to 34 weeks of gestation and beyond is always been challenging, apart from literature and standard text books which advocate individualisation of the management,certain protocols need
Dr. Achanta Vivekanand
doaj
A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study. [PDF]
BACKGROUND: Pre-eclampsia/eclampsia are leading causes of maternal mortality and morbidity, particularly in low- and middle- income countries (LMICs). We developed the miniPIERS risk prediction model to provide a simple, evidence-based tool to identify ...
Jennifer A Hutcheon +118 more
core +2 more sources
Objectives To determine the prevalence of antioxidant micronutrient deficiencies in pregnant women with pre-eclampsia and healthy pregnant women, and to assess the relationships between trace element deficiency in pregnancy and the severity of pre ...
Joseph Tochukwu Enebe +2 more
doaj +1 more source
Hypertensive disorders of pregnancy: a systematic review of international clinical practice guidelines. [PDF]
BACKGROUND: Clinical practice guidelines (CPGs) are developed to assist health care providers in decision-making. We systematically reviewed existing CPGs on the HDPs (hypertensive disorders of pregnancy) to inform clinical practice.
Pels, A +30 more
core +1 more source
Altered placental expression of kisspeptin and its receptor in pre-eclampsia [PDF]
Kisspeptin, originally identified as metastatin, important in preventing cancer metastasis, has more recently been shown to be important in pregnancy.
Williams, Paula Juliet +3 more
core +1 more source
Inflammation and pre-eclampsia
Pre-eclampsia is a common and potentially dangerous disorder of human pregnancy. The maternal syndrome of hypertension, proteinuria and oedema is part of a severe systemic inflammatory response that includes leukocyte and endothelial cell activation.
Borzychowski, A, Sargent, I, Redman, C
openaire +3 more sources

