Results 111 to 120 of about 282,749 (285)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Sunflower under conventional and organic farming systems: results from a long term experiment in Central Italy [PDF]

, 2006
Sunflower productivity under organic and conventional agricultural systems was studied between 2002 and 2004 in the frame of the MASCOT experiment (Mediterranean Arable Systems COmparison Trial), established in 2001.
Antichi, D, Barberi, P, Belloni, P, Cerrai, D, Mazzoncini, M   +4 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Correction: Effects of sorghum residue in presence of pre-emergence herbicides on emergence and biomass of Echinochloa colona and Chloris virgata. [PDF]

PLoS One, 2022
Mobli A, Rinwa A, Sahil, Chauhan BS.
europepmc   +1 more source

Phytotoxicity resulting from pre-emergence graminicides in sorghum [PDF]

South African Journal of Plant and Soil, 2006
This study was prompted by sorghum (Sorghum bicolor (L.) Moench) producers reporting phytotoxicity when using graminicides under unfavourable environmental conditions. A greenhouse experiment was conducted in which five graminicides were evaluated at two temperature regimes, using 10 cultivars. Registered dosage rates of an acetochlo-atrazine-propazine
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Pre-emergence herbicides for weed control in walnuts

California Agriculture, 1967
Walnuts are California's leading deciduous tree crop. Walnut orchardists spend over one million dollars annually for weed control on an estimated 140,000 acres.
A Lange, B Day, L Jordan, R Russell
doaj  

Weed Response to Different Tank-Mix Herbicide Combinations and its Impact on Winter Rice Performance in Zero Till Non-Puddled Condition

Fundamental and Applied Agriculture
Tank-mixture of two or more chemical groups of either pre- or post-emergence herbicide might play a vital role to manage weeds of a diversified community more effectively than their single or sequential application.
A K M Mominul Islam, Md. Abu Said, Mirfatun Rhaman, Israt Jahan, Sabina Yeasmin, Mahmudul Hasan, Mst. Motmainna, Md. Parvez Anwar   +7 more
doaj   +1 more source

Field-Evolved ΔG210-ppo2 from Palmer Amaranth Confers Pre-emergence Tolerance to PPO-Inhibitors in Rice and Arabidopsis. [PDF]

Genes (Basel), 2022
Carvalho-Moore P, Rangani G, Langaro AC, Srivastava V, Porri A, Bowe SJ, Lerchl J, Roma-Burgos N.   +7 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source