Results 71 to 80 of about 8,261,594 (295)

Minimum Acceptable Diet, Anthropometric Failure and Correlates among Children Aged 6-23 Months in a Rural Area of Murshidabad, West Bengal

National Journal of Community Medicine
Background: Minimum acceptable diet (MAD), one of eight core indicators for infant and young child feeding (IYCF), is measured through minimum dietary diversity and minimum meal frequency. MAD is also a determinant for anthropometric failure.
Debayan Dey, Ritu Ghosh, Dilip Kumar Das, Monojit Das   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry [PDF]

, 2019
[Abstract] Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the potential contribution of PP in ...
Macarie, Cezar,, Laroche, Cécile, Bonapace, Stefano,, Maggioni, Aldo P.,, Crespo-Leiro, Maria G., Ulf Dahlström, Maggioni, Aldo P, Andrea Rossi, Piepoli, Massimo F.,, Andrew J.S. Coats, Pier Luigi Temporelli, Maria G. Crespo‐Leiro, Malek, Filip, Tavazzi, Luigi,, Temporelli, Pier Luigi, Crespo-Leiro, María Generosa, Rossi, Andrea,, Rossi, Andrea, Stefano Bonapace, Cécile Laroche, Crespo-Leiro, Maria G.,, Bonapace, Stefano, Malek, Filip,, Dahlström, Ulf, Temporelli, Pier Luigi,, Coats, Andrew J S, Massimo F. Piepoli, Piepoli, Massimo F, Macarie, Cezar, Coats, Andrew J. S.,, Coats, Andrew J. S., Laroche, Cecile,, Filip Malek, Crespo Leiro, Marisa, Cezar Macarie, Luigi Tavazzi, Maggioni, Aldo P., Dahlström, Ulf,, Tavazzi, Luigi, Aldo P. Maggioni, Piepoli, Massimo F.   +40 more
core   +1 more source

Is compromised intestinal barrier integrity responsible for the poor prognosis in critically ill patients with pre-existing hyperglycemia?

Diabetology & Metabolic Syndrome, 2022
Background Compromised intestinal barrier integrity can be independently driven by hyperglycemia, and both hyperglycemia and intestinal barrier injury are associated with poor prognosis in critical illness.
Yi-Feng Wang, Feng-Ming Liang, Min Liu, Li-Cheng Ding, Jiao-Jie Hui, Hong-Yang Xu, Li-Jun Liu   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Utility of gadoxetate disodium-enhanced magnetic resonance imaging in evaluating liver failure risk after major hepatic resection

Quantitative Imaging in Medicine and Surgery
Background Post-hepatectomy liver failure (PHLF) is still a predominant cause of hepatectomy-related mortality. However, it is difficult to evaluate the remnant liver functional reserve accurately before surgery to prevent PHLF.
Qian-Jun Yu, Yu-Chuan Luo, Zhi-wei Zuo, Chuan Xie, Ting-Yu Yang, Tao Wang, Long Cheng   +6 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Pre-mRNA mis-splicing of sarcomeric genes in heart failure

, 2019
Pre-mRNA splicing is an important biological process that allows production of multiple proteins from a single gene in the genome, and mainly contributes to protein diversity in eukaryotic organisms.
Zhilong Chen (424599), Wei Guo (6419322), Chaoqun Zhu (6419296)   +2 more
core   +1 more source

Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. [PDF]

, 2014
Heart failure is common in older people and its prevalence is increasing. The Heart 'omics' in AGEing (HOMAGE) project aims to provide a biomarker approach that will improve the early diagnosis of heart failure.
Rocca, Hans-Peter Brunner-La, Heymans, Stephane, Staessen, JA, Pocock, Stuart, Zannad, Faiez, Bauters, C, Brunner-La Rocca, Hans-Peter; id_orcid, Thijs, Lutgarde, Heymans, S, Cleland, J.G., Pocock, S, Staessen, Jan A., Mebazaa, A, Delles, C, Thijs, L, Masson, Serge, Bauters, Christophe, Kuznetsova, Tatiana, Tomaschitz, A, McDonald, K, Pinet, Florence, Collier, T, Mamas, Mamas, Pinet, F, Jacobs, Lotte, Mebazaa, Alexandre, Sever, P, Jin, Yu, Cleland, JG, Kuznetsova, T, Latini, Roberto, Rouet, P, Mamas, M, Cleland, John G F, Sever, Peter, Jin, Y, Latini, R, Delles, Christian, Rouet, Philippe, Brunner-La Rocca, Hans-Peter, Zannad, F, Brunner-La Rocca, HP, Jacobs, L, Pieske, Burket, Diez, Javier, Diez, J, Cleland, John GF, Masson, S, McDonald, Kenneth, Pieske, B, Staessen, Jan A, Cleland, John G.F., Rocca, HP, Collier, Timothy, Tomaschitz, Andreas, Pieske, Burkert   +55 more
core   +1 more source

Effects of Prospective Audit and Feedback in Patients with Extended-Spectrum β-Lactamase-Producing Escherichia coli Bacteremia

Microorganisms
Antimicrobial stewardship (AS) Guidelines by the Infectious Diseases Society of America recommend employing prospective audit and feedback (PAF) as an effective intervention in AS programs.
Yota Yamada, Motoyasu Miyazaki, Hisako Kushima, Hitomi Hirata, Arata Ogawa, Yukie Komiya, Chika Hagiwara, Akio Nakashima, Hiroshi Ishii, Osamu Imakyure   +9 more
doaj   +1 more source