Results 81 to 90 of about 172,940 (266)

On failure indicators in multi-dissipative materials

open access: yes, 1996
Multi-dissipative constitutive descriptions of irreversible material degradation result in tangent operators that are made up of multiple rank-one updates of the elasticity tensors: multisurface elastoplasticity, plastic yielding combined with elastic ...
Kaspar Willam   +5 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Some Measures of Financial Fragility in the Chilean Banking System: An Early Warning Indicators Application [PDF]

open access: yes
There is an ample literature whose main subject is to build models able to anticipate or provide some early warning signals of problematic financial institutions.
Antonio Ahumada, Carlos Budnevich
core  

Combining clinical markers can predict mortality in NYHA IV heart failure

open access: yesScientific Reports
Early assessment of heart failure during treatment can improve patient prognosis. Brain natriuretic peptide (BNP), uric acid (UA), pre-albumin (PA), red blood cell distribution width (RDW), and Cystatin C (Cys C) are related to the development of heart ...
Yi-jiao Men   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A Review of the Literature on Early Warning Systems for Banking Crises [PDF]

open access: yes
This paper presents a review of alternative methodologies for early detection of banking distress. The methodologies proposed are aimed to the early identification of financial distress for countries without an important recent history of bank failure ...
Alejandro Gaytán, Christian A. Johnson
core  

Conceptualising failure in social marketing [PDF]

open access: yes, 2022
Social marketing concerns how people live their lives and how behaviour may be changed to benefit society – it is, by definition, part of the fabric of life.
Lawson, A., Akbar, M. B.
core  

Damage evolution in marble under uniaxial compression monitored by Pressure Stimulated Currents and Acoustic Emissions

open access: yesFracture and Structural Integrity, 2019
The spatiotemporal evolution of damage in marble speci­mens under uniaxial compression is monitored using Pressure Stimulated Currents (PSCs) and Acoustic Emissions (AEs). The novelty of the study is the use of an integrated grid of sensors (instead of a
Ilias Stavrakas   +2 more
doaj   +3 more sources

Connection of pre-competition anxiety with gut microbiota and metabolites in wrestlers with varying sports performances based on brain-gut axis theory

open access: yesBMC Microbiology
Objective The purpose of this study is to investigate the connection of pre-competition anxiety with gut microbiota and metabolites in wrestlers with different sports performances.
Pengyu Fu   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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