Results 31 to 40 of about 1,895 (169)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Q345C weld deformation analysis of butt joints
Metalurgija, 2023 Q345C steel is welded under two different pre-welding heating methods of traditional flame heating and ceramic sheet heating. The finite element analysis of the butt joint weldment by ABAQUS software is used to summarize the law of welding deformation ...
Y. Z. Zhong +5 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Pre-heating in the framework of massive gravity
Nuclear Physics B, 2016 In this paper we propose a mechanism of natural pre-heating of our universe by introducing an inflaton field dependent mass term for the gravitational wave for a specific class of massive gravity theory.
Debaprasad Maity
doaj +1 more source
Influence of heat treatment on the microwave absorption properties of flaky carbonyl iron powder
International Journal of Lightweight Materials and Manufacture, 2020 High-energy ball milling is a very common method to produce materials with high magnetic permeability due to its ability to produce flaky shape particles on the nano-scale. It is an efficient technique to improve microwave absorbing properties. Therefore,
Hongyu Wei +8 more
doaj +1 more source
Preheating procedure for fast start-up of a steam turbine from a cold state [PDF]
E3S Web of Conferences, 2019 The paper describes a procedure that allows to start up a steam turbine in a significantly shorter period. The procedure is developed for start-ups that begin from a cold state, when the temperature of the parts of the turbine is close to the ambient ...
Kosman Wojciech, Rusin Andrzej
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source