Results 41 to 50 of about 1,895 (169)

Effects of short heating periods during egg storage on quail embryonic development, incubation performance, chick quality, and chick performance up to 35 days

Semina: Ciências Agrárias
This study investigated the effects of pre-heating fertile Japanese quail eggs during storage on embryonic development, incubation performance, hatched chick quality, and chick performance up to 35 days of age.
Marinha Ximenes de Lima Oliveira, Aires Santos Silva, Marcos Adriano Pereira Barbosa, Tatiana Carlesso dos Santos   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Scheduled Pre-Heating of Li-Ion Battery Packs for Balanced Temperature and State-of-Charge Distribution

Energies, 2020
Lithium-ion batteries exhibit significant performance degradation such as power/energy capacity loss and life cycle reduction in low-temperature conditions.
Hien Vu, Donghwa Shin
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Study of oxygen permeation and molecular structure evolution during pre-oxidation of pitch-based carbon fibers

矿业科学学报
Pre-oxidation is attributed to a gas-solid state reaction where oxygen diffuses from the fiber surface to its core along the radial direction. This process is inherently slow, time-consuming, and energy-intensive.
HAN Xue, AN Xiaoya, LI Youwang, QIU Huijun, LIANG Dingcheng, XIE Qiang, LIU Jinchang   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The effect of layer’s moisture content and pre-heating by microwave radiation on physical and mechanical properties of laminated veneer lumber [PDF]

Iranian Journal of Wood and Paper Industries, 2017
The effect of moisture and pre-heating time by the microwave radiation were studied on the physical and the mechanical properties of laminate veneer lumber (LVL).The variable factors included moisture content of layers in the range of 3, 5 and 8 ...
Mohammad Farajallahpour, mohammad layeghi, kazem Dosthosseini, hanidreza edalat   +3 more
doaj  

Influence of egg pre-storage heating period and storage length on incubation results

Brazilian Journal of Poultry Science, 2008
This experiment aimed at evaluating the influence of different heating times of settable eggs of Cobb 500® broiler breeders before submitting them to different storage periods on egg weight loss, embryo mortality, and hatchability.
FHA Silva, DE Faria, KAA Torres, DE Faria Filho, AAD Coelho, VJM Savino   +5 more
doaj   +1 more source