Results 121 to 130 of about 14,388,284 (282)

Chemically peculiar stars on the pre-main sequence [PDF]

Context. The chemically peculiar (CP) stars of the upper main sequence are defined by spectral peculiarities that indicate unusual elemental abundance patterns in the presence of diffusion in the calm, stellar atmospheres.
Faltová, N., Jadlovský, D., Svačinková, K., M. Vítková, Xia, C., Hümmerich, S., Vítková, M., S. Hümmerich, L. Kueß, M. Mesarč, Kueß, L., N. Faltová, M. Labaj, Ramezani, T., K. Svačinková, K. Bernhard, P. Mondal, Mesarč, M., Mondal, P., Prišegen, M., D. Jadlovský, C. Xia, E. Paunzen, J. Supíková, Supíková, J., Bernhard, K., M. Prišegen, Paunzen, E., Labaj, M., T. Ramezani   +29 more
core   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Two Young Eclipsing Binaries in Orion with Temperatures and Radii Affected by Spots and Third Bodies

The Astronomical Journal
In this work we present a model of two young eclipsing binaries in the Orion complex. Both heavily spotted, they present radii and temperatures that are in disagreement with the predictions of standard stellar models.
Marina Kounkel, Keivan G. Stassun
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Bringing the Norma Dark Cloud to Light in X-Rays

The Astronomical Journal
The filamentary dark cloud complex in Norma reveals signs of active low-mass star formation including protostars, H α emission line stars, Herbig–Haro objects, and the eruptive FU Orionis-like star V346 Nor.
Stephen L. Skinner, Manuel Güdel, Luisa M. Rebull   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Separating Photospheric and Starspot Magnetic Fields in Pre-main-sequence Stars Using IGRINS Spectroscopy

The Astrophysical Journal Letters
Magnetic fields in pre-main-sequence (PMS) stars regulate angular momentum evolution, drive magnetic activity, and modify stellar structure, yet their surface distributions remain poorly constrained.
Facundo Pérez Paolino, Lynne A. Hillenbrand, Jeffrey S. Bary   +2 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source