Results 81 to 90 of about 14,388,284 (282)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Submillimeter Variability in the Envelope and Warped Protostellar Disk of the Class 0 Protostar HOPS 358

The Astrophysical Journal
The James Clerk Maxwell Telescope (JCMT) Transient Survey recently discovered that the Class 0 protostar HOPS 358 decreased in 350 GHz continuum brightness by ∼25% over the course of 4 yr before brightening again for the next 4.
Patrick D. Sheehan, Doug Johnstone, Carlos Contreras Peña, Seonjae Lee, Gregory Herczeg, Jeong-Eun Lee, Steve Mairs, John J. Tobin, Hyeong-Sik Yun, The JCMT Transient Team   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

First JVLA Radio Observation on PDS 70

The Astrophysical Journal
PDS 70 is a protoplanetary system that hosts two actively accreting gas giants, namely, PDS 70b and PDS 70 c. The system has a ∼60–100 au dusty ring that has been resolved by the Atacama Large Millimeter/Submillimeter Array (ALMA), along with ...
Hauyu Baobab Liu, Simon Casassus, Ruobing Dong, Kiyoaki Doi, Jun Hashimoto, Takayuki Muto   +5 more
doaj   +1 more source

Pulsational instability of pre-main-sequence models from accreting protostars

, 2021
Context. The picture of pre-main-sequence evolution is often simplified by the application of classical initial models. Such models have large initial radii and sufficient uniform contraction to make them fully convective, however, real stars are born as
E. I. Vorobyov, T. Steindl, K. Zwintz, T. G. Barnes, M. Müllner   +4 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Are there pre-main-sequence/black hole X-ray binaries?

, 2019
<p>MESA inlists associated with <a href="https://ui.adsabs.harvard.edu/#abs/2018MNRAS.480.3856X/abstract">Are there pre-main-sequence/black hole X-ray binaries?</a></p ...
Xu, Xiao-Tian (6446228), Li, Xiang-Dong, Xu, Xiao-Tian, Li, Xiang-Dong (6446231)   +3 more
core   +1 more source

A Distributed Population of Low-Mass Pre-Main-Sequence Stars near the Taurus Molecular Clouds [PDF]

, 2006
We present a drift-scan survey covering a ~5° × 50° region toward the southern portion of the Taurus-Auriga molecular cloud. Data taken in the B,R,I filters with the Quest-2 camera on the Palomar 48 inch (1.2 m) Samuel Oschin Telescope were combined with
Mamajek, Eric E., Catherine L. Slesnick, Lynne A. Hillenbrand, Eric E. Mamajek, Carpenter, John M., Hillenbrand, Lynne A., John M. Carpenter, Slesnick, Catherine L.   +7 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

JWST Reveals Carbon-rich Chemistry in a Transitional Disk

The Astronomical Journal
We present JWST-MIRI Medium Resolution Spectrometer observations of the Classical T Tauri stars GM Aur and RX J1615.3-3255 (J1615), both hosting transitional disks.
M. Volz, C. C. Espaillat, C. V. Pittman, S. L. Grant, T. Thanathibodee, M. McClure, B. Tabone, N. Calvet, F. M. Walter   +8 more
doaj   +1 more source