Results 131 to 140 of about 226,792 (352)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

The initial period function of late-type binary stars and its variation

, 2011
The variation of the period distribution function of late-type binaries is studied. It is shown that the Taurus--Auriga pre-main sequence population and the main sequence G dwarf sample do not stem from the same parent period distribution with better ...
Adams, Brandner, Connelley, Covino, de Zeuw, Duchêne, Duchêne, Duchêne, Duquennoy, Durisen, Fischer, Fisher, Ghez, Goodwin, Hillenbrand, Horton, Kouwenhoven, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Kroupa, Köhler, Köhler, Köhler, Leinert, Luhman, M. G. Petr-Gotzens, Makarov, Mathieu, Maury, Mayor, McCaughrean, Moeckel, Nakajima, P. Kroupa, Parker, Perryman, Petr, Preibisch, Prosser, Raghavan, Ratzka, Reipurth, Richichi, Salim, Simon, Simon, Sterzik, Wichmann   +51 more
core   +1 more source

Lithium Depletion in Fully Convective Pre-Main-Sequence Stars [PDF]

, 1996
We present an analytic calculation of the thermonuclear depletion of lithium in contracting, fully convective, pre-main-sequence stars of mass M ≲ 0.5 M☉. Previous numerical work relies on still uncertain physics (atmospheric opacities and convection, in
L. Bildsten, E. Brown, C. Matzner, G. Ushomirsky   +3 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Magnetism, rotation and accretion in Herbig Ae-Be stars

, 2007
Studies of stellar magnetism at the pre-main sequence phase can provide important new insights into the detailed physics of the late stages of star formation, and into the observed properties of main sequence stars.
Blondel, Bouret, C. Catala, C. Folsom, Catala, Catala, Catala, Catala, Catala, Collier Cameron, E. Alecian, G.A. Wade, Hubrig, J. Grunhut, J.-C. Bouret, J.-F. Donati, J.D. Landstreet, Landi, Lignières, Morel, Natta, P. Petit, S. Bagnulo, Stepień, Stepień, T. Boehm, Thé, Wade   +27 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Disk-locking Regulates Stellar Rotation in Young Clusters: Insights from NGC 2264

The Astrophysical Journal
Many young clusters possess extended main sequences, a phenomenon commonly ascribed to stellar rotation. However, the mechanism behind their very wide stellar rotation distributions remains unclear.
Yutian Bu, Chenyu He, Min Fang, Chengyuan Li   +3 more
doaj   +1 more source

On the ages of pre-main-sequence stars in Taurus

The Astronomical Journal, 1992
A search for pre-main-sequence stars in a region of about 12.7 deg 2 near the L 1551 complex in the Taurus molecular cloud have been made. Only two new pre-main-sequence stars have been identified from optical spectra of 383 proper motion candidates on the basis of Li I 6707 A absorption.
I. N. Reid, John Stauffer, B. F. Jones, R. Hewett, Lee Hartmann, Mercedes Gomez, Scott J. Kenyon   +6 more
openaire   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Gaia23bab: A New EXor

The Astrophysical Journal
On 2023 March 6, the Gaia telescope alerted a 2 mag burst from Gaia23bab, a young stellar object in the Galactic plane. We observed Gaia23bab with the Large Binocular Telescope obtaining optical and near-infrared spectra close in time to the peak of the ...
T. Giannini, E. Schisano, B. Nisini, P. Ábrahám, S. Antoniucci, K. Biazzo, F. Cruz-Sáenz de Miera, E. Fiorellino, M. Gangi, A. Kóspál, M. Kuhn, E. Marini, Z. Nagy, D. Paris   +13 more
doaj   +1 more source