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Regulation of Alternative Pre-mRNA Splicing
2014Alternative splicing plays a prevalent role in generating functionally diversified proteomes from genomes with a more limited repertoire of protein-coding genes. Alternative splicing is frequently regulated with cell type or developmental specificity and in response to signaling pathways, and its mis-regulation can lead to disease.
Miguel B, Coelho, Christopher W J, Smith
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Regulation of mammalian pre-mRNA splicing
Science in China Series C: Life Sciences, 2009In eukaryotes, most protein-coding genes contain introns which are removed by precursor messenger RNA (pre-mRNA) splicing. Alternative splicing is a process by which multiple messenger RNAs (mRNAs) are generated from a single pre-mRNA, resulting in functionally distinct proteins.
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GnRH pre-mRNA splicing: role of exonic splicing enhancer
2002Publisher Summary This chapter discusses gonadotropin-releasing hormone (GnRH) pre-mRNA splicing. GnRH plays a key role in the regulation of reproduction. It is synthesized in the preoptic area (POA) of the vertebrate brain and released from nerve terminals in the median eminence into the hypothalamic-pituitary portal vessel in a pulsatile fashion ...
Jin, Han +3 more
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1994
This chapter is focused on the splicing of nuclear pre-mRNAs in higher plants. Other aspects of plant mRNA processing such as polyadenylation and mRNA stability are discussed in recent reviews.1, 2 Nothing is known about the localization of pre-mRNA processing events in the plant nucleus or mRNA transport to the cytoplasm.
Witold Filipowicz +3 more
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This chapter is focused on the splicing of nuclear pre-mRNAs in higher plants. Other aspects of plant mRNA processing such as polyadenylation and mRNA stability are discussed in recent reviews.1, 2 Nothing is known about the localization of pre-mRNA processing events in the plant nucleus or mRNA transport to the cytoplasm.
Witold Filipowicz +3 more
openaire +1 more source
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
exaly

