Results 111 to 120 of about 4,690,273 (294)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Positive effects of pre-oxidation on high temperature oxidation behavior of TiAl composites with multilayered structure

Journal of Materials Research and Technology
In order to study the pre-oxidation on high temperature oxidation behavior of TiAl composites with high-efficiency, the TiAl composites with multilayered structure were successfully prepared via spark plasma sintering (SPS) by introducing 0.5 wt% BN, 0.5 
Junqin Wu, Yupeng Wang, Genhua Zeng, Xiaohong Wang, Lei Li, Meng Li, Tengfei Ma   +6 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Study on the Pre-Oxidation and Resulting Oxidation Mechanism and Kinetics of Mo-9Si-8B Alloy. [PDF]

Materials (Basel), 2021
Wang C, Li Q, Guo Z, Li X, Ding X, Li X, Li Z, Li B.   +7 more
europepmc   +1 more source

Oxidation features of plastic deformed Zr-based bulk metallic glass

, 2011
The surface morphology of in situ deformed, pre-deformed, undeformed and crystallized Zr(47.9)Ti(0.3)Ni(3.1)Cu(39.3)Al(9.4) bulk metallic glass in air at elevated temperatures are investigated to improve the understanding of the effect of plastic ...
李磊, Wei, BC (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China, 邢建硕, 魏炳忱, 胡燕萍, 胡铮, Lei Li, Zheng Hu, Jianshuo Xing, Bingchen Wei, Yanping Hu   +10 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Superior oxidation resistance in air during hot stamping of a coating-free press-hardened steel achieved by pre-oxidation

Journal of Materials Research and Technology
While coating-free press-hardened steel (CF-PHS) can prevent high-temperature oxidation during hot stamping, it requires high-purity nitrogen protection, which increases the operation cost.
Zhao Li, Lingyu Wang, Zhou Wang, Jianfeng Wang, Wei Xu   +4 more
doaj   +1 more source

The Songhua River Chemical Pre-Oxidation of Potassium Permanganate

, 2011
The use of potassium permanganate on the micro-pollutants in the Songhua River water for pre-oxidation, the results showed: potassium permanganate oxidation of organic compounds in water on the Songhua River (CODMn, UV254, TOC) has better removal effect;
Jin Long Zuo, Zhi Wei Zhao, Jun Sheng Li
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source