Results 51 to 60 of about 1,797,796 (318)

SMP30 Interacts with ROCK1 to Inhibit HCC Invasiveness by Effecting the Epithelial-Mesenchymal Transition

Frontiers in Bioscience-Landmark
Background: The senescence marker protein 30 (SMP30) is a calcium-binding protein whose expression decreases with age, and is closely associated with hepatocellular carcinoma (HCC) development.
Shunxin Zheng, Zhijing Mo, Zhilue Lv, Yuan Zhuang, Sufang Zhou   +4 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Prevalencia de protozoos intestinales en 79 niños de 2 a 5 años de edad de un hogar infantil estatal en Circasia, Quindío Prevalence of intestinal Protozoa in79 Children 2 to 5 years old from a state nursery in Circasia, Quindío

Infectio, 2010
Introducción: Los parásitos intestinales se consideran un problema de salud pública en los países en desarrollo y afecta a individuos de todas las edades y sexos, pero se presentan, sobre todo, en los primeros años de vida.
Jonathan Andrés Arias, Gloria Elcy Guzmán, Fabiana María Lora-Suárez, Elizabeth Torres, Jorge Enrique Gómez   +4 more
doaj  

Bioinformatic analyses and validated experiments reveal an aging hallmark gene set and protective miR of coronary artery disease

Scientific Reports
To investigate how aging hallmarks exert roles in the age-related disease of coronary artery disease (CAD). R software and the GEO2R online tool identified differentially expressed genes (DEGs) and differentially expressed microRNAs (DEMis) in CAD ...
Jing Chen, Hai-Zhen Huang, Hua-Yu Wu, Gui-Ding Wang, Jin-Long Deng, Dong-Feng Wu, Li-Na Wen, Lan-Lan Qiu, Chen-Xi Cui, Chong-Yang Song, Shang-Ling Pan   +10 more
doaj   +1 more source

English speaking training based on local wisdom to support the English language skills

Research and Development in Education
English language skills are essential skills that must be mastered by people in today's digital era, including students. However, students' ability to speak English is still low as evidenced by the results of the UKBing test for Campus 3 students at ...
S. Surayanah, M. Anas Thohir, Lilik Bintartik, Marsanda Avilia Putri, L. Lestariningsih   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Proposing a contextual approach to pre-school teacher education in Ghana

Cogent Education, 2016
Efforts of Ghanaian Universities and Colleges of Education in training pre-school teachers have been found inadequate and unable to meet their training needs.
Nana Yaa A. Nyarko, C. Charles Mate-Kole
doaj   +1 more source

Validity, practical utility, and reliability of the activPAL in preschool children [PDF]

, 2012
<p>Purpose: With the increasing global prevalence of childhood obesity, it is important to have appropriate measurement tools for investigating factors (e.g. sedentary time) contributing to positive energy balance in early childhood. For pre-school
Aminian, AMY J. MCGOWAN, Arvidsson, Bailey, Bland, Busser, Bussmann, Cole, de Onis, Foerster, Ford, Franks, Freeman, Godfrey, Grant, Guo, GWYNETH DAVIES, Healy, Hu, Jackson, JAMES Y. PATON, JOHN J. REILLY, Langer, Lanningham-Foster, Lyons, Mackey, MALCOLM H. GRANAT, Mathie, Najafi, Paraschiv-Ionescu, Penpraze, PHILIPPA M. DALL, Reilly, Ryan, Steinberger, Trost, Uiterwaal, White, Zhang   +38 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

The influence of family cultural capital on student learning engagement: a study on the mediating role of parental educational involvement

Frontiers in Psychology
IntroductionIn the digital era, the role of family in education is increasingly prominent. While cultural capital theory offers a framework for understanding educational inequality, the dynamic conversion of new forms of family cultural capital, such as ...
Juanjuan Zang, Pengfei Chen
doaj   +1 more source