Results 51 to 60 of about 1,634,376 (219)

Bioinformatic analyses and validated experiments reveal an aging hallmark gene set and protective miR of coronary artery disease

Scientific Reports
To investigate how aging hallmarks exert roles in the age-related disease of coronary artery disease (CAD). R software and the GEO2R online tool identified differentially expressed genes (DEGs) and differentially expressed microRNAs (DEMis) in CAD ...
Jing Chen, Hai-Zhen Huang, Hua-Yu Wu, Gui-Ding Wang, Jin-Long Deng, Dong-Feng Wu, Li-Na Wen, Lan-Lan Qiu, Chen-Xi Cui, Chong-Yang Song, Shang-Ling Pan   +10 more
doaj   +1 more source

The Influence of Georgia’s Quality Rated System on School Readiness in Pre-School Children

Journal of the Georgia Public Health Association, 2016
Background: Georgia rates the quality of early childcare learning centers using a tiered quality improvement system. Georgia’s Quality Rated system (QR) designates a star level, (one star, two stars or three stars) to each center based on a portfolio of ...
Dena Phillips, Nancy Webb
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Traditional and modern forms of cooperation between kindergarden and family: towards a network society

Rozprawy Społeczne
The diagnostic survey method was used. The research covered a group of 122 teachers from selected preschool institutions of the Lubelskie Voivodship and 122 parents. The results show that traditional forms of cooperation, i.e.
Joanna Waszczuk, Barbara Struk, Anna Sawczuk   +2 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Smartphone Dependency Among Young Learners: A Growing Concern

Profesi Pendidikan Dasar
This comparative quantitative study examined smartphone addiction rates among children using a modified Smartphone Addiction Questionnaire, focusing on differences between preschool and primary school students to inform prevention and health promotion ...
Prilya Shanty Andrianie, Rosita Yuniati, Wahdan Najib Habiby, Nurwanto Nurwanto   +3 more
doaj   +1 more source

Health-related knowledge and preferences in low socio-economic kindergarteners

International Journal of Behavioral Nutrition and Physical Activity, 2012
Objective The aim of the present study was to determine physical activity (PA) and nutrition knowledge and preferences in low socio-economic status kindergarten children.
Nemet Dan, Geva Deganit, Meckel Yoav, Eliakim Alon   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Reading Acquisition Among 5- to 6-Year-Old Children in the Programme of Compulsory Preparation for School

Discourse and Communication for Sustainable Education, 2010
In the context of compulsory education for 5-6 year-old children, the question about reading acquisition is one of fundamental concerns for both pre-school teachers and parents.
Zariņa Sandra
doaj   +1 more source