Results 61 to 70 of about 13,025,887 (300)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Rozprawy SpołeczneThe diagnostic survey method was used. The research covered a group of 122 teachers from selected preschool institutions of the Lubelskie Voivodship and 122 parents. The results show that traditional forms of cooperation, i.e.
Joanna Waszczuk +2 more
doaj +1 more source
The Influence of Georgia’s Quality Rated System on School Readiness in Pre-School Children
Journal of the Georgia Public Health Association, 2016 Background: Georgia rates the quality of early childcare learning centers using a tiered quality improvement system. Georgia’s Quality Rated system (QR) designates a star level, (one star, two stars or three stars) to each center based on a portfolio of ...
Dena Phillips, Nancy Webb
doaj +1 more source
Aulad, 2020 Recent studies have revealed that English has become a global language that is commonly used, particularly in the education sector, for various purposes.
Aisyah Khaleeda Rosli +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Scientific ReportsTo investigate how aging hallmarks exert roles in the age-related disease of coronary artery disease (CAD). R software and the GEO2R online tool identified differentially expressed genes (DEGs) and differentially expressed microRNAs (DEMis) in CAD ...
Jing Chen +10 more
doaj +1 more source
Pre-School Education and Attainment in the NCDS and BCS [PDF]
This paper considers the effect of how children pass time before entrance to school on attainment in primary school. We find in NCDS data that children perform marginally better at seven and eleven if they spent time with their mother, or at a pre-school,
Donald Robertson +2 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Smartphone Dependency Among Young Learners: A Growing Concern
Profesi Pendidikan DasarThis comparative quantitative study examined smartphone addiction rates among children using a modified Smartphone Addiction Questionnaire, focusing on differences between preschool and primary school students to inform prevention and health promotion ...
Prilya Shanty Andrianie +3 more
doaj +1 more source
Giving children a better start: preschool attendance and school-age profiles [PDF]
, 2006 We study the effect of pre-primary education on children's subsequent school outcomes by exploiting a unique feature of the Uruguayan household survey (ECH) that collects retrospective information on preschool attendance.
Manacorda, M. +8 more
core +1 more source