Results 81 to 90 of about 13,025,887 (300)

Pre-school and early home learning effects on A-level outcomes: effective Pre-school, Primary & Secondary Education Project (EPPSE)

, 2015
Research into the ‘Effective pre-school, primary and secondary education’ (EPPSE) project and A level ...
Toth, K., Sammons, P., Iraj, I., Taggart, B., Melhuish, Edward C., Sylva, K.   +5 more
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pembelajaran Holistik–Integratif Anak Usia Dini dengan Pendekatan Cashflow Quadrant di RA Al Muttaqin Tasikmalaya

Al-Athfal: Jurnal Pendidikan Anak, 2017
This article is aimed to figure out the integrative holistic learning process of early childhood which consist of implementation of child health service program, education, child welfare protection, nad child care.
Yuli Salis Hijriyani, Imam Machali
doaj   +1 more source

Effective pre-school, primary and secondary education project (EPPSE 3-14) : students' reports of their experiences in year 9 [PDF]

, 2011
The Effective Pre-school, Primary and Secondary Education Project (EPPSE) has inves tigated the academic and social behavioural (+ in the later stages the affective) development of approximately 3,000 children from the age of 3+ years since 1997.
Smees, R., Draghici, D., Smees, R, Siraj-Blatchford, Iram, Toth, Katalin, Taggart, Brenda, Taggart, B., Sylva, K., Melhuish, E, Sammons, Pam, Sammons, P., Siraj-Blatchford, I, Sammons, Pamela, Draghici, Diana, Sammons, P, Draghici, D, Smees, Rebecca, Sylva, K, Sylva, Kathy, Toth, K, Toth, K., Siraj-Blatchford, I., Melhuish, Edward, Melhuish, Edward C., Taggart, B   +24 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Supporting mathematical giftedness in pre-school and primary education: a systematic literature review

Eesti Haridusteaduste Ajakiri
Kaasaegses andekuspedagoogikas on fookus nihkunud andekate tuvastamiselt arengut toetava keskkonna loomisele. Artikli eesmärk on anda ülevaade alus- ja alghariduses rakendatud tõenduspõhistest matemaatilise andekuse arengut toetavatest sekkumistest ...
Karin Konksi, Merle Taimalu, Karin Täht
doaj   +1 more source

The influence of school and teaching quality on children’s progress in primary school [PDF]

, 2008
This report investigates the way school and classroom processes affect the cognitive progress and social/behavioural development of children between the ages of 6 (Year 1) and 10 (Year 5) in primary schools in England.
Barreau, S., Taggart, B., Sylva, K., Grabbe, Y., Siraj-Blatchford, I., Sammons, P., Melhuish, Edward C.   +6 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The construction of “the competent child” and early childhood care

Educare, 2008
The phenomenon I focus on in this article is the construction of “the competent child”, which has developed from both psychology and later the sociology of childhood and has influenced the Swedish Childhood Education.
Annika Månsson
doaj