Results 201 to 210 of about 51,859 (300)

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Modulatory effects of ketamine on EEG source-based resting state connectivity in treatment resistant depression. [PDF]

Transl Psychiatry
Lees T, Scott JN, Boyle BW, Esfand SM, Linton SR, Miller C, Li M, Woronko SE, Dunayev R, Bogdanov M, Bolton P, Li S, Meisner RC, Pizzagalli DA.   +13 more
europepmc   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Power Pixels: a turnkey pipeline for processing of Neuropixel recordings. [PDF]

Peer Community J
Meijer GT, Battaglia FP.
europepmc   +1 more source

Follicular growth and plasma progesterone patterns in Bos indicus x Bos taurus heifers submitted to different PGF2a/progesterone-based synchronization protocols [PDF]

AYRES, H., BARUSELLI, P.S., BÓ, G. A, MANTOVANI, A.P., NICHI, M., SÁ FILHO, M.F., VETTORATO, L.F.   +6 more
core  

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Individual neural dynamics of successful Gamma neuromodulation through EEG-neurofeedback in the aging brain. [PDF]

Sci Rep
Houmani N, Yabouri R, Garcia-Salicetti S, Bedoin M, Medani T, Andrade K.   +5 more
europepmc   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Neurogranin Promotes Neuronal Maturation and Network Activity Through Ca²⁺/Calmodulin Signaling. [PDF]

Int J Mol Sci
Martínez-Blanco E, de Andrés R, López-Merino E, Esteban JA, Díez-Guerra FJ.   +4 more
europepmc   +1 more source