The Impact of Vertical Sleeve Gastrectomy on Behavioral and Reward-Related Outcomes. [PDF]
Brain BehavVertical sleeve gastrectomy (VSG) produces robust and consistent metabolic improvements in diet‐induced obese male mice. However, post‐surgical behavioral, reward‐related, and cognitive outcomes may be dependent on dietary context, as VSG reduces operant responding for sucrose under high‐fat diet maintenance but yields no significant behavioral changes
R J +11 more
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vsgseq2: an updated pipeline for analysis of the diversity and abundance of population-wide Trypanosoma brucei VSG expression [version 1; peer review: 2 approved] [PDF]
Wellcome Open ResearchTrypanosoma brucei is an extracellular eukaryotic parasite that causes sleeping sickness in humans and Nagana, Surra and Dourine in livestock, game animals and horses.
Stephen Larcombe +4 more
doaj +2 more sources
Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies. [PDF]
PLoS Pathogens, 2016 The extracellular bloodstream form parasite Trypanosoma brucei is supremely adapted to escape the host innate and adaptive immune system. Evasion is mediated through an antigenically variable Variant Surface Glycoprotein (VSG) coat, which is recycled at ...
Jackie L Y Cheung +5 more
doaj +1 more source
Turnover of Variant Surface Glycoprotein in
mBio, 2021 African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous GPI-specific phospholipase C (
Paige Garrison +9 more
doaj +1 more source
Vertical sleeve gastrectomy induces distinctive transcriptomic responses in liver, fat and muscle
Scientific Reports, 2021 Vertical sleeve gastrectomy (VSG) is the most commonly performed bariatric/metabolic surgery, exhibiting a high rate of diabetes remission in humans. To elucidate the molecular mechanisms of VSG, we performed transcriptomic analysis of the liver, fat ...
Chang Ho Ahn +5 more
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IET Smart Grid, 2020 In this study, virtual excitation emulation (VEE) is proposed along with the virtual inertia emulation (VIE) for a virtual synchronous generator (VSG) in a standalone microgrid to improve the AC voltage and frequency profile through the control of power ...
Soumya Samanta +3 more
doaj +1 more source
Escaping the immune system by DNA repair and recombination in African trypanosomes [PDF]
Open Biology, 2019 African trypanosomes escape the mammalian immune response by antigenic variation—the periodic exchange of one surface coat protein, in Trypanosoma brucei the variant surface glycoprotein (VSG), for an immunologically distinct one.
Núria Sima +3 more
doaj +1 more source
Energies, 2023 Virtual synchronous generators (VSG) are considered a new generation of grid-friendly inverters with the same inertial support characteristics as synchronous generators (SG). However, the inertia support comes with the side effects of power and frequency
Hao Liu +4 more
doaj +1 more source
Pathogens, 2021 Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, Variant Surface Glycoprotein (VSG), to evade the host immune response.
Bibo Li, Yanxiang Zhao
doaj +1 more source
SUMOylation by the E3 ligase TbSIZ1/PIAS1 positively regulates VSG expression in Trypanosoma brucei. [PDF]
PLoS Pathogens, 2014 Bloodstream form trypanosomes avoid the host immune response by switching the expression of their surface proteins between Variant Surface Glycoproteins (VSG), only one of which is expressed at any given time.
Diana López-Farfán +3 more
doaj +1 more source