Results 71 to 80 of about 1,386,765 (307)

Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice [PDF]

, 2017
Surgical or genetic disruption of vomeronasal organ (VNO)-accessory olfactory bulb (AOB) function previously eliminated the ability of male mice to processes pheromones that elicit territorial behavior and aggression.
Baum, Michael J., Cherry, James A., Doctor, Danielle, Han, Xue, Korzan, Wayne J., Kunkhyen, Tenzin, McCarthy, Elizabeth A.   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Historical background to the formation of the forensic doctrine on neutralising investigation counteraction

Bulletin of Kharkiv National University of Internal Affairs
The article substantiates that in the course of historical development of mankind, counteraction to an investigation naturally accompanies such a form of social activity as criminal activity, and therefore, is a substantive component of criminal activity.
O. M. Tarkan
doaj   +1 more source

Self-Hypnosis for Intrapartum Pain management (SHIP) in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness [PDF]

, 2015
Objective: (Primary): to establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use Design: Multi-method RCT Setting: Three NHS Trusts Population: Nulliparous women not planning elective caesarean,
Ali, Shehzad, Diggle, Peter, Downe, Soo, Finlayson, Kenneth, Gyte, Gill, Hinder, Susan, Melvin, Cathie, Miller, Vivien, Slade, Pauline, Spiby, Helen, Treppel, Dominic, Weeks, Andrew, Whorwell, Peter, Williamson, Maria   +13 more
core   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Tinjauan Yuridis Penetapan Tersangka sebagai Objek Praperadilan (Studi kasus Putusan Mahkamah Konstitusi Nomor: 21/PUU-XII/2014) [PDF]

, 2018
This study aims to determine the object of pre-trial post-Constitutional Court decision which adds the determination of the suspect as a pretrial object regulated by Criminal Procedure Code.
, Hartanto, S.H., M.Hum, Narimo, Agung
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Проблеми застосування інституту зупинення досудового провадження у діяльності слідчих органів внутрішніх справ [PDF]

, 2012
Татаров О. Ю. Проблеми застосування інституту зупинення досудового провадження у діяльності слідчих органів внутрішніх справ / О. Ю. Татаров // Актуальні проблеми політики : зб. наук. пр. / редкол. : С. В. Ківалов (голов. ред..), Л. І.
Tatarov, О., Татаров, О. Ю., Татаров, О. Ю.   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source