Results 81 to 90 of about 9,867,009 (304)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The article deals with problematic issues related to the appointment and conducting of engineering and technical expertise in specialty 10.23 «Investigation of the technical condition and operating conditions of machines and mechanisms.» It is also noted
Ігор Стельмашов
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Detention as a violation of the fundamental right to protection
Purpose. The purpose of the work is to study the current legislation that violates a person’s fundamental right to protection when the preventive measure of detention is chosen for him. Method.
Lototskyi M., Dzundza L.
doaj +1 more source
This is an excellent handbook for lawyers and judges in the newly developed art of pre-trial. Over the last fifteen years there has been a steadily increasing interest in pre-trial conferences. Conducted by the judge with counsel before the actual trial,
Clark, Charles
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Disclosure of evidence in pre-trial proceedings and investigation [PDF]
Disclosure of evidence to the defendant and defense counsel during pre-trial proceedings and investigations is important for the defendant to be able to devise a defense strategy and to suggest the taking of other evidentiary actions during the ...
Živković Natalija M.
doaj
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Columbia Accident Investigation Board Report: Volume 4. Other Technical Documents
Fourth volume of the final report produced by the Columbia Accident Investigation Board including documents produced by NASA and other organizations which were provided to the Columbia Accident Investigation Board in support of its inquiry into the ...
Columbia Accident Investigation Board
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