Results 101 to 110 of about 9,640,698 (298)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Book Review: Pre-Trial

open access: yes, 1951
This is an excellent handbook for lawyers and judges in the newly developed art of pre-trial. Over the last fifteen years there has been a steadily increasing interest in pre-trial conferences. Conducted by the judge with counsel before the actual trial,
Clark, Charles
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Prosecutor´s role in the pre-trial proceedings

open access: yes, 2013
V této práci se primárně věnuji charakterizaci a systematizaci jednotlivých oprávnění a povinností státního zástupce v přípravném řízení. V úvodních kapitolách práce se zabývám obecným úvodem do problematiky.
Gorská, Veronika
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Victim in pre-trial criminal proceedings

open access: yes, 2013
Bakalaura darba tēma ir „Cietušais pirmstiesas kriminālprocesā”. Autore uzskata, ka cietušais kā pirmstiesas kriminālprocesa dalībnieks ieņem vienu no būtiskākajām vietām kriminālprocesā, jo parasti cietušais ir viens no galvenajiem informātoriem un ...
Švaikovska, Jeļena
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Fast-track pre-trial proceedings

open access: yes, 2015
This thesis deals with the institute of summary preliminary proceedings in the context of past and current legislation and also the reasons that led to its introduction into law.
Trojanová, Monika
core  

Grounds and conditions for the application of preventive measures during the pre-trial investigation of corruption criminal offenses

open access: yesLaw and Safety
The article is devoted to clarifying the content of the grounds and conditions for the application of preventive measures during the pre-trial investigation of corruption criminal offenses.
V. V. Romaniuk, R. I. Login
doaj   +1 more source

INTERRELATION OF PROCEDURAL DECISIONS IN PRE-TRIAL PROCEEDINGS

open access: yesBulletin of the South Ural State University series "Law"
A procedural decision, as an element of criminal procedure, ensures the dynamics of criminal proceedings and is made by officials under the influence of external and internal factors, which in practice lead to a distorted perception of the interconnectedness of procedural decisions and their development into procedural interdependence.
openaire   +1 more source

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