Results 71 to 80 of about 96,102 (259)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Judicial Responses to Pre-Trial Procedural Violations in International Criminal Proceedings
, 2018 This book provides an in-depth examination of the judicial response at the international criminal tribunals (ICTs) to the violation of procedural standards in the pre-trial phase of proceedings.
Kelly Pitcher, Pitcher, Kelly.
core +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Disclosure of evidence in pre-trial proceedings and investigation [PDF]
Strani pravni život, 2020 Disclosure of evidence to the defendant and defense counsel during pre-trial proceedings and investigations is important for the defendant to be able to devise a defense strategy and to suggest the taking of other evidentiary actions during the ...
Živković Natalija M.
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Minor victim in pre-trial criminal proceedings
, 2016 Darba tēma: Nepilngadīgais cietušais pirmstiesas kriminālprocesā. Bakalaura darba mērķis ir izpētīt nepilngadīgā cietušā statusu un lomu pirmstiesas kriminālprocesā Latvijā, kā arī atrast ar šo jautājumu saistīto problemātiku, kuru izvērtēt un rast tās ...
Pastare, Laura
core
DETENTION CONTROL IN PRE-TRIAL CRIMINAL PROCEEDINGS
Detention is the most severe security measure, which is applied to the suspect or the accused person in pre-trial criminal proceedings. Due to the significiantly restrictive nature of human rights, a systematic review of the legality of detention is ...
Zalužinska , Inga
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Efficiency of criminal procedure and adjustment of pre-trial proceedings [PDF]
, 2014 v anglickém jazyce Efficiency of criminal procedure and adjustment of pre-trial proceedings The purpose of my thesis is to analyse relationship between basic principles of criminal procedure and the purpose of criminal procedure.
Marková, Ljuba
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source