Results 101 to 110 of about 8,264 (228)

Post‐surgery level of circulating DNA in stage III colon cancer patients: Impact on the reliability of minimal residual disease detection

International Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.
What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev, Saidi Daoud, Catalina Isabel Cofre Muñoz, Alexia Mirandola, Ekaterina Pisareva, Javier Gonzalo Ruiz, Marco Macagno, Nadia Saoudi Gonzalez, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry   +17 more
wiley   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani, Nina Bono, Alice Caldiroli, Stefania Adele Riboldi, Gabriele Candiani   +4 more
wiley   +1 more source

An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper (R) [PDF]

, 2017
Background: Accurate determination of the predictive markers human epidermal growth factor receptor 2 (HER2/ERBB2), estrogen receptor (ER/ESR1), progesterone receptor (PgR/PGR), and marker of proliferation Ki67 (MKI67) is indispensable for therapeutic ...
A Goldhirsch, AC Wolff, Andreas Turzynski, Annette Lebeau, Arndt Hartmann, B Rosner, C Criscitiello, C Denkert, Claudia Gürtler, DA Cohen, E Azambuja de, EA Rakha, Elena Guerini-Rocco, F Cardoso, FL Baehner, Fraser Symmans, Frederique Penault-Llorca, Giuseppe Viale, Heikki Joensuu, Hong Bu, International Electrotechnical Commission, J Cuzick, J Gerdes, JA Sparano, JL Fleiss, JMS Bartlett, JMS Bartlett, John Bartlett, JR Landis, Kornelia Schlombs, L Harris, LN Harris, M Dowsett, M Dowsett, M Eliasziw, M Laible, M Lee, M Schobesberger, Mark Laible, MC Polley, MC Polley, MEH Hammond, N Wolmark, O Gluz, Peter Schraml, Peter Sinn, R Yerushalmi, Reinhard von Wasielewski, RJ McEnroe, RM Wirtz, Robert Stoehr, SCY Leung, SM Teutsch, T Kirkegaard, T Nielsen, Thomas Keller, Ugur Sahin, Xiaodong Teng, Z Varga, Z Varga, Zsuzsanna Varga   +60 more
core   +5 more sources

Exploring alternatives to tumor tissue for BRCA1/2 next‐generation sequencing testing in high‐grade serous ovarian cancer: A 34‐case series of malignant ascites

Cancer Cytopathology, Volume 134, Issue 5, May 2026.
Abstract Background BRCA1/2 testing is currently recommended at diagnosis for high‐grade serous ovarian carcinoma (HGSOC) because of its impact on patients' survival when treated with poly(adenosine diphosphate ribose) polymerase inhibitors. Standard clinical practice involves analyzing BRCA1/2 genes in formalin‐fixed, paraffin‐embedded (FFPE ...
Chiara Pighi, Giulio Settanni, Marta Angelini, Laura Bortesi, Valeria Viassolo, Marcello Ceccaroni, Francesco Bruni, Stefania Gori, Gian Franco Zannoni, Anna Pesci   +9 more
wiley   +1 more source

AMH standardization and preanalytical phase as two sides of the same coin. [PDF]

JBRA Assist Reprod, 2023
Demirci G, Saçıntı KG, Sönmezer M, Öztürk HS.   +3 more
europepmc   +1 more source

Defining a roadmap for harmonizing quality indicators in Laboratory Medicine: A consensus statement on behalf of the IFCC Working Group "laboratory Error and Patient Safety" and EFLM Task and Finish Group "performance specifications for the extra-analytical phases" [PDF]

, 2016
The improving quality of laboratory testing requires a deep understanding of the many vulnerable steps involved in the total examination process (TEP), along with the identification of a hierarchy of risks and challenges that need to be addressed.
Sciacovelli, Laura, Panteghini, Mauro, Lippi, Giuseppe, Sumarac, Zorica, Cadamuro, Janne, Galoro, César Alex De Olivera, Pino Castro, Isabel Garcia Del, Shcolnik, Wilson, Plebani, Mario   +8 more
core   +4 more sources

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1205-1215, May 2026.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco, Troy D. Wood, Raymond Cha, Jill S. Hochreiter, Susan L. Rosenkranz, Mona Farhad, Kyle R. Whitson, Connor E. Gould, Lauren E. Hill, Linda L. Hale, Philip H. Lindhorst, Diala Ghazal, Charlene R. Taylor, Madiha Quraishi, Suzanne M. Siminski, Yoninah Cramer, Heather L. Sprenger, Gene D. Morse   +17 more
wiley   +1 more source

Preanalytical errors in emergency department samples: Investigating error sources [PDF]

Journal of Medical Biochemistry, 2020
Background: The presence of preanalytical errors is a recurring fact in all areas of healthcare that send samples to laboratories. Increasing the knowledge of possible sources of error in the preanalytical phase has been the objective of this group ...
Romero Adolfo, Gómez-Salgado Juan, Romero-Arana Adolfo, Gómez-Fernández José Antonio, Cobos Andrés, Ramos María Carmen, Iglesias María Rosa   +6 more
doaj  

GC × GC‐TOF MS and Sensory Profiling of Aroma Compounds in Magnolia Species: Effects of Processing Methods on Volatile Retention in M. wufengensis

Flavour and Fragrance Journal, Volume 41, Issue 3, Page 487-503, May 2026.
The first comparative analysis of Magnolia scents reveals that M. wufengensis is characterised by a high aldehyde content, exhibiting a fresh, sweet, and fruity fragrance profile. Furthermore, freeze‐drying preserves 6.7 times more 2‐nonenal compared to shade‐drying, highlighting its superior efficacy in retaining key volatile compounds.
Xiaole Wang, Zhonghua Du, Lei Xu, Junjie Hu, Tao Xiong, Chiqing Chen, Lichun Ye, Zhaohua Shi   +7 more
wiley   +1 more source

Impact and frequency of IV fluid contamination on basic metabolic panel results using quality metrics

Journal of Laboratory Medicine
Clinical laboratories invest substantial time and resources to mitigate measurement error but potential errors during the preanalytical phase of testing are not subjected to the same level of scrutiny. Herein, we assess the proportions of intravenous (IV)
Spies Nicholas C., Farnsworth Christopher W.   +1 more
doaj   +1 more source