Results 31 to 40 of about 3,889 (166)

The impact of different preanalytical methods related to CA 15-3 determination in frozen human blood samples: a systematic review

open access: yesSystematic Reviews, 2021
Background The determination of CA 15-3 is useful for monitoring breast cancer patients. Several retrospective studies determined CA 15-3 levels in frozen samples to evaluate the sensitivity and specificity of novel biomarkers in relation to breast ...
Luigi Coppola   +5 more
doaj   +1 more source

Enzyme immunoassay in the practice of a physician

open access: yesКлинический разбор в общей медицине, 2022
Enzyme linked immunosorbent assay (ELISA) plays an important role in various fields of medicine. It is currently the most accessible laboratory technique. The article discusses the basic principles of solid-phase ELISA, its most famous modifications. The
Oksana V. Moskalets
doaj   +1 more source

A novel multimodal approach for the assessment of phlebotomy performance in nurses

open access: yesJournal of Laboratory Medicine, 2023
Phlebotomy is presumably the most challenging preanalytical aspect in laboratory medicine. In Europe, inpatient phlebotomy is performed by nurses in 45–60 % of cases. We aimed to develop and test a novel phlebotomy assessment tool for nurses.
Oprea Oana Roxana   +2 more
doaj   +1 more source

Enhancing Quality in Hematology Laboratory Testing: A Comprehensive Review of Preanalytical Phase Errors and Prevention Strategies

open access: yesJournal of Applied Hematology
This comprehensive review explores the critical importance of the preanalytical phase in hematology laboratory testing and its significant impact on the overall quality of results.
Pooja Dattatray Mankar   +4 more
doaj   +1 more source

Determining the rate and reasons for specimen rejection among specimens referred for HIV viral load determination through referral linkage to Debre Tabor Comprehensive Specialized Hospital, north-central, Ethiopia,2023: Retrospective study

open access: yesHeliyon
Background: The preanalytical phase encompasses the time between the clinician's test order to the sample being ready for analysis. Of all errors during the laboratory diagnostic process,70 % appeared in the pre-analytical phase. In clinical laboratories,
Ayenew Berhan   +6 more
doaj   +1 more source

Improving wound swab collection in paediatric patients: a quality improvement project

open access: yesBMJ Open Quality, 2023
Microbiology sample swabs may be unsuccessful or rejected for a variety of reasons. Typically, errors occur in the preanalytical phase of sample collection. Errors with collection, handling and transport can lead to the need to repeat specimen collection.
Ian Chin-Yee   +4 more
doaj   +1 more source

MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai   +8 more
wiley   +1 more source

Unveiling the hidden clinical and economic impact of preanalytical errors

open access: yesTürk Biyokimya Dergisi
The preanalytical phase is the basis upon which the accuracy and reliability of laboratory testing mostly depend. Despite many recent advancements in laboratory medicine, preanalytical errors remain the most common source of diagnostic inaccuracies ...
Lippi Giuseppe
doaj   +1 more source

Biomarkers of Endothelial Damage in Acute Graft‐Versus‐Host Disease After Allogenic Hematopoietic Stem Cell Transplantation: Methodological Challenges

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Allogeneic hematopoietic stem cell transplantation remains a potentially curative therapy for many hematological malignancies; however, its success is significantly limited by acute graft‐versus‐host disease (aGVHD), a leading cause of post‐transplant morbidity and mortality in which endothelial dysfunction plays a central role.
Katarina Klinar, Helena Podgornik
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

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