Results 51 to 60 of about 5,347 (236)

The impact of different preanalytical methods related to CA 15-3 determination in frozen human blood samples: a systematic review

Systematic Reviews, 2021
Background The determination of CA 15-3 is useful for monitoring breast cancer patients. Several retrospective studies determined CA 15-3 levels in frozen samples to evaluate the sensitivity and specificity of novel biomarkers in relation to breast ...
Luigi Coppola, Alessandra Cianflone, Katia Pane, Monica Franzese, Peppino Mirabelli, Marco Salvatore   +5 more
doaj   +1 more source

Preanalytical quality improvement - an interdisciplinary journey, on behalf of the European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE)

, 2022
Since the beginning of laboratory medicine, the main focus was to provide high quality analytics. Over time the importance of the extra-analytical phases and their contribution to the overall quality became evident.
Lewis, Tom,, Von Meyer, Alexander,, Ibarz, Mercedes, Simundic, Ana-Maria, Baumann, Gabriele, Bolenius, Karin, Baumann, Gabriele,, Plebani, Mario, Cornes, Michael, Bölenius, Karin,, Lippi, Giuseppe, Ibarz, Mercedes,, Cornes, Michael,, Baird, Geoffrey,, Baird, Geoffrey, Oliveira, Gabriel Lima, Oliveira, Gabriel Lima,, Cadamuro, Janne, Lewis, Tom, Plebani, Mario,, von Meyer, Alexander, Simundic, Ana-Maria,, Cadamuro, Janne,, Lippi, Giuseppe,   +23 more
core   +1 more source

Determining the rate and reasons for specimen rejection among specimens referred for HIV viral load determination through referral linkage to Debre Tabor Comprehensive Specialized Hospital, north-central, Ethiopia,2023: Retrospective study

Heliyon
Background: The preanalytical phase encompasses the time between the clinician's test order to the sample being ready for analysis. Of all errors during the laboratory diagnostic process,70 % appeared in the pre-analytical phase. In clinical laboratories,
Ayenew Berhan, Andargachew Almaw, Shewaneh Damtie, Yenealem Solomon, Biruk Legese, Birhanu Getie, Mulat Erkihun   +6 more
doaj   +1 more source

Improving wound swab collection in paediatric patients: a quality improvement project

BMJ Open Quality, 2023
Microbiology sample swabs may be unsuccessful or rejected for a variety of reasons. Typically, errors occur in the preanalytical phase of sample collection. Errors with collection, handling and transport can lead to the need to repeat specimen collection.
Ian Chin-Yee, Sean H Leonard, Johan Delport, Abby Crozier, Farah Abdulsatar   +4 more
doaj   +1 more source

The CRESS checklist for reporting stability studies: on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

Clinical Chemistry and Laboratory Medicine, 2020
To ensure that clinical laboratories produce results that are both accurate and of clinical utility it is essential that only samples of adequate quality are analysed.
M. Cornes, A. Šimundić, J. Cadamuro, S. Costelloe, G. Baird, Gunn B. B. Kristensen, A. von Meyer, M. Nybo, Rubén Gómez Rioja   +8 more
semanticscholar   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun, Jing Zhang, Chenqing Liu, Jing Lou, Sihui Wang, Xiangtian Ji, Xiaofang Zhao, Shirui Xu, Jingyu Feng, Bin Liu, Chao Chang, Qinggang Ge, Jun Yang   +12 more
wiley   +1 more source

Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai, Isabel Pinto Amorim das Virgens, Ádám Vincze, Mahmoud Obeidat, Péter Hegyi, Mikolt Bakony, Zsófia Réka Erdélyi, Zsolt Melczer, Sándor Valent   +8 more
wiley   +1 more source

Recommendations for blood sampling in emergency departments from the European Society for Emergency Medicine (EUSEM), European Society for Emergency Nursing (EuSEN), and European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase. Executive summ

Clinical Chemistry and Laboratory Medicine
Aim Blood Sampling Guidelines have been developed to target European emergency medicine-related professionals involved in the blood sampling process (e.g.
Luis Garcia-Castrillo, J. Cadamuro, Christoph Dodt, D. Lauwaert, Said Hachimi-Idrissi, C. van der Linden, Jochen Bergs, SJ Costelloe, Florian F. Grossmann, Ayça Koca, Ari Palomäki, J. L. Ruiz, R. Stonys, T. Thorsteinsdottir, A. von Meyer, P. Vermeersch, Maria Concepción Abellas Alvarez, Pinar Eker, Adela Golea, Lisa Kurland, Giuseppe Lippi, Yulia Zhilenkova, K. Sehmi   +22 more
semanticscholar   +1 more source

Improving the preanalytical process: the focus on specimen quality [PDF]

Journal of Medical Biochemistry, 2008
Trends in clinical laboratory practice place more demands on the quality of patient specimens. Advances in analytical performance (i.e., increased automation, reduced sample volume, increased assay sensitivity), as well as efficiency and cost reduction ...
Green Sol
doaj