Results 51 to 60 of about 4,353 (174)

Preanalytical factors affecting the plasma and serum levels of circulating microRNAs

Кардиоваскулярная терапия и профилактика
Circulating microribonucleic acids (microRNAs) are promising biomarkers of various diseases, but their clinical laboratory use requires highly sensitive, reproducible, reliable and sustainable methods for their accurate plasma and serum quantification ...
E. A. Sotnikova, A. V. Kiseleva, A. N. Meshkov   +2 more
doaj   +1 more source

Continual Improvement in Clinical Bacteriology Laboratory with Quality Indicators: A Retrospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Healthcare management is undergoing significant changes with the evolution of new and re-emerging infections. A clinical microbiologist plays an important role in giving an accurate and timely report to the clinicians.
Mrudul Randive, Desma D Souza, Alka Shinde, Madhurima Nair, Ankita Chaurasia, Ashima Jamwal, Sujata Chavan, Sujata Baveja   +7 more
doaj   +1 more source

From prediction to intervention: Causal artificial intelligence as the missing link in precision therapeutics

Precision Medical Sciences, EarlyView.
Predictive multiomics artificial intelligence (AI) identifies risk but does not indicate which intervention will change a patient's outcome; causal AI, anchored in biological mechanism, bridges this gap to enable individualized treatment decisions.
Gedion Mengistu Dejen
wiley   +1 more source

Quality indicators of the pre-analytical phase [PDF]

Journal of Medical Biochemistry, 2012
Quality indicators are tools that allow the quantification of quality in each of the segments of health care in comparison with selected criteria. They can be defined as an objective measure used to assess the critical health care segments such as, for ...
Majkić-Singh Nada, Šumarac Zorica
doaj  

Plasma Steroid Trajectories From Day‐of‐Surgery Baseline After Robot‐Assisted Radical Prostatectomy for Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Circulating steroid trajectories after robot‐assisted radical prostatectomy are poorly characterized from the day‐of‐surgery baseline, and relevant biology extends beyond testosterone and dihydrotestosterone to adrenal‐derived 11‐oxygenated androgens and steroid conjugate turnover.
Jiri Heracek, Lukas Gadus, Michal Horenitzky, Marie Novakova, Tereza Skodova, Lucie Kolatorova, Anezka Varausova, Adela Lukaskova, Jana Vitku   +8 more
wiley   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Comparison of plasma separation techniques prior to freezing on equine immunoreactive adrenocorticotrophic hormone

Equine Veterinary Education, EarlyView.
Summary Background Pituitary pars intermedia dysfunction (PPID) is the most common endocrine disorder affecting older horses and is commonly diagnosed by measurement of basal plasma adrenocorticotrophic hormone (ACTH) concentration. Current guidelines advise that whole blood or gravity‐separated plasma samples must not be frozen prior to analysis ...
L. J. Hughes, A. E. Durham, C. A. Maile
wiley   +1 more source

Plasma amylin levels in migraine and after erenumab treatment: A REFORM study

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Researchers are searching for blood tests that can show what is happening in migraine and help predict who will benefit from preventive treatment, and blood amylin (a signaling molecule known to trigger migraine) has been shown to be elevated in people with chronic migraine.
Rogelio Domínguez‐Moreno, Tyla I. Alexander, William K. Karlsson, Haidar M. Al‐Khazali, Michael L. Garelja, Rune H. Christensen, Messoud Ashina, Debbie L. Hay, Håkan Ashina   +8 more
wiley   +1 more source

Misidentification and other preanalytical errors [PDF]

Journal of Medical Biochemistry, 2008
The largest number of laboratory errors occur in the preanalytical phase and are mainly due to educational and organizational reasons. The experience of our institution, as well as the results of an Italian interlaboratory effort to detect and reduce ...
Bonini Pierangelo, Ceriotti Ferruccio, Mirandola Gaia, Signori Chiara   +3 more
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