Results 71 to 80 of about 5,347 (236)

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p.A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

Movement Disorders, EarlyView.
Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis, Christos Koros, Athina‐Maria Simitsi, Leonidas Stefanis, and The Parkinson's Progression Markers Initiative, Kenneth Marek, Tanya Simuni, Andrew Siderowf, Caroline Tanner, Thomas F Tropea, Tatiana Foroud, Lana Chahine, Brit Mollenhauer, Kalpana Merchant, Douglas Galasko, Christopher Coffey, Kathleen Poston, Roseanne Dobkin, Ethan Brown, Roy Alcalay, Dan Weintraub, Emily Flagg, Kimberly Fabrizio, Susan Bressman, Cornelis Blauwendraat, Paola Casalin, Sonya Dumanis, Raymond James, Karl Kieburtz, Sneha Mantri, Werner Poewe, Michael Schwarzschild, John Seibyl, David Standaert, Duygu Tosun‐Turgut, Sohini Chowdhury, Jamie Eberling, Mark Frasier, Leslie Kirsch, Katie Kopil, Maggie Kuhl, Alyssa O'Grady, Todd Sherer, Tawny Willson, Tanya Simuni, Bridget McMahon, Craig Stanley, Kim Fabrizio, Dixie Ecklund, Christine Kohnen, Tatiana Foroud, Laura Heathers, Christopher Hobbick, John Seibyl, Christopher Coffey, Chelsea Caspell‐Garcia, Michael Brumm, Arthur Toga, Karen Crawford, Tatiana Foroud, Jan Hamer, Brit Mollenhauer, Doug Galasko, Kalpana Merchant, Andrew Singleton, Tatiana Foroud, Dirk Keene, Caroline Tanner, Ethan Brown, Carlie Tanner, Ethan Brown, Lana Chahine, Roseann Dobkin, Monica Korell, Neha Prakash, Tanya Simuni, Nabila Dahodwala, Caroline Tanner, Lana Chahine, Brit Mollenhauer, Sebastian Schade, Douglas Galasko, Anat Mirelman, Roy Alcalay, Katherine Leaver, Marie Saint‐Hilaire, Ruth Schneider, Christopher Tarolli, Werner Poewe, Aleksandar Videnovic, David Standaert, Marissa Dean, Sonja Jonsdottir, Rejko Krueger, Claire Pauly, Stewart Factor, Penelope Hogarth, Robert Hauser, Amy Amara, Michelle Fullard, Cyrus Zabetian, Hubert Fernandez, Kathrin Brockmann, Isabel Wurster, Yen Tai, Paolo Barone, Marina Picillo, Stuart Isaacson, Alberto Espay, Eduardo Tolosa, Javier Ruiz Martinez, Leonidas Stefanis, Kelvin Chou, Lorraine Kalia, Connie Marras, David Grimes, Tiago Mestre, Rajesh Pahwa, Mark Lew, Holly Shill, Shyamal Mehta, Giulietta Riboldi, Nikolaus McFarland, Ron Postuma, Zoltan Mari, David Ledingham, Nicola Pavese, Michele Hu, Norbert Brueggemann, Christine Klein, Bastiaan Bloem, Cristina Simonet, Alastair Noyce, Anette Janzen, David Pedrosa, Wolfgang Oertel, Njideka Okubadejo, David Shprecher, Arjun Tarakad, Emile Moukheiber, Joy Antala, Carla Aranda, Karen Williams, Sophia Melton, Karina Benson, Ashwini Ramachandran, Danielle Potts, Grace LaMoure, Ritikha Vengadesh, Ryan Manzler, Jaime Heller, Primi Ranola, Farah Kausar, Sherri Mosovsky, Diana Willeke, Elizabeth Kalinkara Gomez, Janelle Rodriguez, Nobuko Kemmotsu, May Eshel, Deborah Raymond, Abigail Desrosiers, Raymond James, Lauren Jackson, Iris Egner, Wesley Schlett, Courtney Blair, Lauren Ruffrage, Berenice Sevilla, Barbara Sommerfeld, Dustin Le, Erica Botting, Gabriella Mazur, Daniele Derlein, Evan Doll, Ying Liu, Ciera Cobb, Olivia Masiewicz, Jennifer Mule, Michael Morsillo, Ella Hilt, Aldazier Jakiran, Dominga Valentino, Lisbeth Pennente, Bobbie Stubbeman, Alicia Garrido, Valeria Ravasi, Ioana Croitoru, Christos Koros, Nikolas Papagiannakis, Frank Ferrari, Mengyu Zheng, Shawna Reddie, Alicia Alejandra, Andrea Gray, Alejandra Valenzuela, Caitlin Goodman, Sara Dresler, Neil Santos, Fahrial Esha, Kyle Rizer, Nadine Zablith, Liliana Dumitrescu, Debra Galley, Victoria Kate Foster, Jamil Razzaque, Madita Grümmer, Yara Krasowski, Natalie Donkor, Elisabeth Sittig, Oluwadamilola Ojo, Kelly Clark, Rory Mahabir, Kori Ribb, Shamera Willoughby   +213 more
wiley   +1 more source

Evaluation of thyroglobulin autoantibodies in dogs at the time of diagnosis of hypoadrenocorticism and during treatment

Veterinary Record, EarlyView.
Abstract Background Autoimmune thyroiditis (AIT) may occur more frequently in dogs with hypoadrenocorticism (HA) than previously recognised. The objective of this study was to determine the presence of thyroglobulin autoantibodies (TgAAs) in dogs with HA.
Christin Emming, Sina Strey, Ina Leiter, Reinhard Mischke, Holger Volk, Marion Schmicke, Johanna Rieder   +6 more
wiley   +1 more source

A Comprehensive Evaluation of the Preanalytical Phase in Laboratory Medicine, Nephrology, Emergency Specialties, Visceral Surgery, Pediatrics, Internal Medicine and Neonatology Hospital Departments: In-Depth Insights derived from an analysis of practices at a Medical University Centre in Morocco

Jordan Medical Journal
Background and Aims: The precision of biological examination results hinges on meticulous preparatory measures before analysis, known as the pre-analytical phase. This phase contributes significantly to error rates (48-68%).
Oussama Rahhab, E. Sebbar, M. Choukri
semanticscholar   +1 more source

Continual Improvement in Clinical Bacteriology Laboratory with Quality Indicators: A Retrospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Healthcare management is undergoing significant changes with the evolution of new and re-emerging infections. A clinical microbiologist plays an important role in giving an accurate and timely report to the clinicians.
Mrudul Randive, Desma D Souza, Alka Shinde, Madhurima Nair, Ankita Chaurasia, Ashima Jamwal, Sujata Chavan, Sujata Baveja   +7 more
doaj   +1 more source

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Greater efficiency observed 12 months post-implementation of an automatic tube sorting and registration system in a core laboratory [PDF]

Journal of Medical Biochemistry, 2016
Background: Sample classification and registration have been recognized as important and time-consuming processes in laboratories. There is increasing pressure on laboratories to automate processes due to intense workload and reduce manual procedures and
Ucar Fatma, Erden Gonul, Yavuz-Taslipinar Mine, Ozturk Gulfer, Ginis Zeynep, Bulut Erdem, Delibas Namik   +6 more
doaj  

Decoverslipping of Archival Cytology Aspirate Smears for Ancillary Studies: A Review of Methods and Institutional Experience With Freezer‐Based Techniques

Cytopathology, EarlyView.
Freezer‐based decoverslipping of archival cytology aspirate smears achieved only 32.5% slide‐level success (26/80), with mounting medium composition and coverslip material, not freezing temperature or duration, identified as dominant determinants, underscoring the need to align coverslipping practices with anticipated ancillary testing requirements ...
Nyein Nyein Htun, Sinchita Roy‐Chowdhuri, Benjamin B. Morris, Gloria Hopkins Sura   +3 more
wiley   +1 more source

Multicenter Interlaboratory Study of Thrombin Generation Assay in Healthy Adults Using the ST Genesia Analyzer With the STG‐ThromboScreen Reagent (With and Without Thrombomodulin)

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Fully automated thrombin generation (TG) assays facilitate the transition from research to clinical application. We conducted a multicenter inter‐laboratory study using the ST Genesia analyzer to evaluate assay performance and establish reference intervals in healthy adults from Spain and Portugal.
Diego Velasco‐Rodríguez, María Marcos‐Jubilar, Inés Martínez‐Alfonzo, Laura Martos, Carlos Aguilar, Noelia Vilalta, Dolors Llobet, Ana Marco‐Rico, David Aragoneses, Pascual Marco, Luciana Ricca, David Ferreira, Sara Lopes, João Mariano‐Pego, Ángel Bernardo, Antonio Moscardó, Santiago Bonanad, Susana Gassiot, Isabel Gutiérrez‐Jomarrón, Jose Antonio Páramo, Pilar Llamas‐Sillero, Joan Carles Reverter   +21 more
wiley   +1 more source

Breakfast can Affect Routine Hematology and Coagulation Laboratory Testing: An Evaluation on Behalf of COLABIOCLI WG-PRE-LATAM

TH Open, 2019
Laboratories worldwide perform both hematological and coagulation testing on patients avoiding fasting time. In 2017, the Latin America Confederation of Clinical Biochemistry (COLABIOCLI) commissioned the Latin American Working Group for Preanalytical ...
Maria Elena Arredondo, Eduardo Aranda, Rubén Astorga, Lorena Michele Brennan-Bourdon, Marise Danielle Campelo, Silvia Flores, Claudio Medel, Ignacio Manríquez, Patricia Ochoa, Beatriz Varela, Carlos Vega Salinas, Gabriel Lima-Oliveira   +11 more
doaj   +1 more source

BSAVA Petsavers Article: Validation of an ELISA assay for measurement of the metabolite of serotonin, 5‐hydroxyindole acetic acid (5‐HIAA), in canine urine

Journal of Small Animal Practice, EarlyView.
Objectives Serotonin (5‐hydroxytryptophan), implicated in a number of canine diseases, has a very short half‐life in the serum. Urine concentration of its breakdown product 5‐hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans.
D. Castillo, A. Swallow, T. Williams, P. Watson   +3 more
wiley   +1 more source