Results 61 to 70 of about 5,347 (236)

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

The rise in preanalytical errors during COVID-19 pandemic

, 2021
The COVID-19 pandemic has posed several challenges to clinical laboratories across the globe. Amidst the outbreak, errors occurring in the preanalytical phase of sample collection, transport and processing, can further lead to undesirable clinical ...
Trikha, Anjan, Mukhopadhyay, Tapasyapreeti, Arulselvi Subramanian, Anjan Trikha, Pandey, Shivam, Nirupam Madaan, Tapasyapreeti Mukhopadhyay, Madaan, Nirupam, Subramanian, Arulselvi, Shivam Pandey, Rajesh Malhotra, Malhotra, Rajesh   +11 more
core   +1 more source

The effect of preanalytical phase on the stability of the osmotic fragility and morphological changes in erythrocytes in cattle (Bos taurus)

ANIMAL SCIENCE AND GENETICS
Hereditary spherocytosis in cattle is a disorder that results from a nonsense mutation in SLC4A1 gene that encodes band 3 membrane protein. This membranopathy leads to a production of spherically-shaped RBCs with reduced deformability and shorter ...
Piotr Antos, Marta H. Machura
semanticscholar   +1 more source

Preanalytical factors affecting the plasma and serum levels of circulating microRNAs

Кардиоваскулярная терапия и профилактика
Circulating microribonucleic acids (microRNAs) are promising biomarkers of various diseases, but their clinical laboratory use requires highly sensitive, reproducible, reliable and sustainable methods for their accurate plasma and serum quantification ...
E. A. Sotnikova, A. V. Kiseleva, A. N. Meshkov   +2 more
doaj   +1 more source

Establishment and implementation of an improvement plan using Lean Six Sigma methodology to minimize variation in ordering laboratory tests

Journal of the Arab Society for Medical Research, 2022
Background/aim Ordering laboratory (laboratory) tests by physicians is a part of the pre-preanalytical laboratory phase, which is a high error-prone process.
Salwa H Gomaa, Mona M Abaza, Reham M Rashwan, Nabil L Dowidar, Ola H Elgaddar   +4 more
doaj   +1 more source

Biomarkers of Endothelial Damage in Acute Graft‐Versus‐Host Disease After Allogenic Hematopoietic Stem Cell Transplantation: Methodological Challenges

Journal of Clinical Laboratory Analysis, EarlyView.
Allogeneic hematopoietic stem cell transplantation remains a potentially curative therapy for many hematological malignancies; however, its success is significantly limited by acute graft‐versus‐host disease (aGVHD), a leading cause of post‐transplant morbidity and mortality in which endothelial dysfunction plays a central role.
Katarina Klinar, Helena Podgornik
wiley   +1 more source

Quality Indicators in the Preanalytical Phase of Testing in a Stat Laboratory [PDF]

Laboratory Medicine, 2014
To quantify performance in the preanalytical phase in a stat laboratory using quality indicators, and compare our results with those in the literature to improve laboratory services.We counted the test request forms, samples, and the types of preanalytical errors that occured in a stat laboratory between January 1 and December 31, 2011.
Daniela Stefania, Grecu, Daliborca Cristina, Vlad, Victor, Dumitrascu   +2 more
openaire   +2 more sources

Dynamic Prognostic Nutritional Index With Circulating Tumor DNA Predicts Survival in Localized Pancreatic Ductal Adenocarcinoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz, Claire Shen, Dominic J. Vitello, Madison Cox, Amy Wells, Krishay Sridalla, David J. Bentrem, Qiang Zhang, Ishan Roy, Akhil Chawla   +9 more
wiley   +1 more source

Quality indicators of the pre-analytical phase [PDF]

Journal of Medical Biochemistry, 2012
Quality indicators are tools that allow the quantification of quality in each of the segments of health care in comparison with selected criteria. They can be defined as an objective measure used to assess the critical health care segments such as, for ...
Majkić-Singh Nada, Šumarac Zorica
doaj