Results 61 to 70 of about 3,889 (166)

Feasibility of routine clinical liquid‐based cytology for lung cancer compact panel testing

Cancer Cytopathology, Volume 134, Issue 9, September 2026.
Abstract Background The Lung Cancer Compact Panel (cPANEL) is a recently approved highly sensitive multiplex gene panel in Japan that supports both DNA‐ and RNA‐based next‐generation sequencing. Although cytological specimens are acceptable for cPANEL, unfixed cell pellets or dedicated preservation tubes are typically recommended.
Yoshiki Shinomiya, Kanako C. Hatanaka, Asami Okumura, Ayae Nange, Mamiko Yamamoto, Manabu Azuma, Katsuji Marukawa, Yuko Ishida, Tomohiro Shimizu, Ryoko Watanabe, Yamato Hashimoto, Mitsuharu Abiko, Yoshiharu Sato, Jun Sakakibara‐Konishi, Tatsuya Kato, Shinya Tanaka, Yutaka Hatanaka   +16 more
wiley   +1 more source

Greater efficiency observed 12 months post-implementation of an automatic tube sorting and registration system in a core laboratory [PDF]

Journal of Medical Biochemistry, 2016
Background: Sample classification and registration have been recognized as important and time-consuming processes in laboratories. There is increasing pressure on laboratories to automate processes due to intense workload and reduce manual procedures and
Ucar Fatma, Erden Gonul, Yavuz-Taslipinar Mine, Ozturk Gulfer, Ginis Zeynep, Bulut Erdem, Delibas Namik   +6 more
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, Volume 20, Issue 8, Page 2102-2113, August 2026.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The results of a close follow-up of trainees to gain a good blood collection practice [PDF]

Journal of Medical Biochemistry, 2020
Background: Phlebotomy is one of the most important steps in the preanalytical phase of a clinical laboratory process. In order to decrease phlebotomy errors, this specific procedure should be taught in detail by laboratory organizations.
Aykal Güzin, Esen Hatice, Yeğin Ayşenur, Öz Cemile   +3 more
doaj  

Dynamic Prognostic Nutritional Index With Circulating Tumor DNA Predicts Survival in Localized Pancreatic Ductal Adenocarcinoma

Journal of Surgical Oncology, Volume 134, Issue 2, Page 272-281, August 2026.
ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz, Claire Shen, Dominic J. Vitello, Madison Cox, Amy Wells, Krishay Sridalla, David J. Bentrem, Qiang Zhang, Ishan Roy, Akhil Chawla   +9 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

MedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge, Dong Han, Jing Wang, Xinyu Dai, Chen Ma, Feihong Chen   +5 more
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Rules of Blood Sampling and Storage for Laboratory Studies

Общая реаниматология, 2008
Objective: to review and to systematize the recommendations on reducing the incidence of defects occurring with a sample of blood after its sampling in the preanalytical phase and the impact of these shifts on the correct interpretation of a patient ...
A. Ye. Muronov, I. B. Zabolotskikh
doaj   +1 more source

Impact and frequency of IV fluid contamination on basic metabolic panel results using quality metrics

Journal of Laboratory Medicine
Clinical laboratories invest substantial time and resources to mitigate measurement error but potential errors during the preanalytical phase of testing are not subjected to the same level of scrutiny. Herein, we assess the proportions of intravenous (IV)
Spies Nicholas C., Farnsworth Christopher W.   +1 more
doaj   +1 more source