Results 101 to 110 of about 8,556 (220)

Integrative Single‐Cell Analysis Reveals Iron Overload‐Induced Senescence and Metabolic Reprogramming in Ovarian Endometriosis‐Associated Infertility

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Iron overload in ovarian endometriosis (OE) disrupts follicular function and contributes to infertility. This study maps iron‐induced cellular changes using single‐cell and spatial transcriptomics, revealing senescence phenotypes in OE patients and mouse models. Similar patterns are observed in aging ovaries, highlighting iron metabolism as a potential
Yangshuo Li   +14 more
wiley   +1 more source

Control of primordial follicle recruitment by anti-Mullerian hormone in the mouse ovary [PDF]

open access: yes, 1999
The dimeric glycoprotein anti-Mullerian hormone (AMH) is a member of the transforming growth factor-beta superfamily of growth and differentiation factors.
Durlinger, A.L.L. (Alexandra)   +6 more
core   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

open access: yesAdvanced Science, Volume 12, Issue 30, August 14, 2025.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang   +7 more
wiley   +1 more source

Therapeutic Potential of GeGen Decoction for the Treatment of Polycystic Ovary Syndrome

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The efficacy of GGD in PCOS has been evaluated by in vivo and in vitro model. Our findings demonstrated that GGD effectively alleviated PCOS symptoms in rat models by improving estrous cycles, restoring ovarian morphology, regulating hormone levels, and ameliorating glucose and lipid metabolism disorders.
Yiwen Qian   +4 more
wiley   +1 more source

Serine threonine kinase receptor associated protein regulates early follicle development in the mouse ovary. [PDF]

open access: yes, 2017
The molecular mechanisms involved in regulating the development of small, gonadotrophin-independent follicles are poorly understood; however, many studies have highlighted an essential role for TGFB ligands.
Fenwick, M.A.   +4 more
core   +1 more source

Morphological characterization and isolation of preantral follicles in Chianina cows reared in Tuscany

open access: yesItalian Journal of Animal Science, 2011
In the last decade some isolation procedures were developed to obtain an increase in the number of progeny born per dam from a high number of oocytes manipulated in vitro (Telfer, 1996).
A. Giorgetti   +4 more
doaj   +1 more source

Prolonged hypothyroidism severely reduces ovarian follicular reserve in adult rats [PDF]

open access: yes, 2017
Background There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovulation and fertilization rates ...
Keijer, Jaap   +4 more
core   +2 more sources

The art of oocyte meiotic arrest regulation

open access: yesReproductive Biology and Endocrinology, 2019
A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordial germ cells (PGCs)-derived oocyte releases ...
Bo Pan, Julang Li
doaj   +1 more source

Effects of α-tocopherol and ternatin antioxidants on morphology and activation of goat preantral follicles in vitro cultured [PDF]

open access: yes, 2009
Os efeitos do α-tocoferol e da ternatina sobre morfologia, ativação e crescimento de folículos pré-antrais caprinos cultivados in vitro, por um ou cinco dias, foram avaliados.
Bruno, J.B.   +12 more
core   +2 more sources

Dinamika Folikel Ovarium Domba Pascatransplantasi Intrauterin pada Kelinci Pseudopregnanst [PDF]

open access: yes, 2007
The objective of this study was to evaluate the follicle dynamics of ewe ovarium post-intrauterine transplantation to pseudopregnanty rabbit. The experiment was concerned with the 1st or 7th days of pseudopregnancy to receive the ewe ovarium. After 5,
Boediono, A. (Arief)   +3 more
core  

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