Results 91 to 100 of about 8,605 (217)

TFAM‐Mediated mtDNA Replication is Essential for Developmental Competence of In Vitro Grown Oocytes

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose Mitochondria are essential for oocyte maturation and early embryonic development, supplying ATP and maintaining mitochondrial DNA (mtDNA) integrity. During oogenesis, mtDNA undergoes dramatic amplification, but the mechanisms and functional significance of this process remain unclear. The purpose of this study was to elucidate the role
Son Quang Do, Hidetaka Tasaki, Hiroaki Funahashi, Takuya Wakai   +3 more
wiley   +1 more source

Biology and Biotechnology of Follicle Development

The Scientific World Journal, 2012
Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development.
Gustavo Adolfo Palma, Martin Eduardo Argañaraz, Antonio Daniel Barrera, Daniela Rodler, Adrian Ángel Mutto, Fred Sinowatz   +5 more
doaj   +1 more source

Morphometry and immunohistochemistry of follicles growth and steroidogenesis in saharian wild sand rat, Psammomys obesus, ovary.

Folia Histochemica et Cytobiologica, 2010
The sand rat (Psammomys obesus) constitutes a model to study seasonal changes and several metabolic disorders. In order to perform breeding laboratory conditions, the reproductive function of this species living in North Occidental Algerian Sahara was ...
Jean-Marie Exbrayat, Farida Khammar, ThĂŠrese Gernigon-Spychalowicz, Amina Boubekri   +3 more
doaj   +1 more source

Autoimmune Thyroid Disease and Female Fertility: Clinical Evidence on Ovarian Reserve, Infertility Treatment Outcomes, and Pathophysiology

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
Thyroid autoimmunity may exert a subtle influence on ovarian reserve through complex endocrine and immune mechanisms, with age‐specific variation. Although AMH alterations are observed, their clinical relevance for primary ovarian insufficiency, fertility, and treatment outcomes of assisted reproduction remains unclear, highlighting the need for ...
Akira Iwase, Yuko Hasegawa, Yoshikazu Kitahara, Seung Chik Jwa, Hiromitsu Shirasawa, Michio Kitajima, Yukiko Katagiri, Harada Miyuki, Kawamura Kazuhiro, Satoko Osuka   +9 more
wiley   +1 more source

Development of antral follicles after xenografting of isolated small human preantral follicles

Reproductive BioMedicine Online, 2008
Small human pre-antral follicles can be enzymatically isolated from the surrounding stroma, and are able to survive after 7 days of xenografting. The aim of the present study was to assess the developmental capacity of enzymatically isolated human follicles after long-term xenografting to severe combined immunodeficient (SCID) mice.
Marie-Madeleine, Dolmans, Wu Yuan, Yuan, Alessandra, Camboni, Antoine, Torre, Anne, Van Langendonckt, Belen, Martinez-Madrid, Jacques, Donnez   +6 more
openaire   +2 more sources

The Role of Anethole in Reproductive Physiology and In Vitro Biotechnologies—A Review

Reproduction in Domestic Animals, Volume 61, Issue 1, January 2026.
ABSTRACT In vitro reproductive biotechnologies show promise for fertility preservation but still face challenges, including oxidative stress from high oxygen tension, which impairs cell viability and development. Antioxidants have been widely explored to attenuate oxidative stress during culture.
André Luiz da Conceição‐Santos, José Ricardo de Figueiredo   +1 more
wiley   +1 more source

Canine preantral follicles cultured with various concentrations of follicle-stimulating hormone (FSH)

Theriogenology, 2010
The objective was to evaluate the effects of various concentrations of exogenous FSH during in vitro culture of isolated canine preantral follicles. Preantral secondary follicles (>200 microm) were isolated by microdissection and cultured for 18 d in supplemented alpha-Minimum Essential Medium (alpha-MEM).
Michelle Karen Brasil, Serafim, Valdevane Rocha, Araújo, Gerlane Modesto, Silva, Ana Beatriz Graça, Duarte, Anderson Pinto, Almeida, Roberta Nogueira, Chaves, Cláudio Cabral, Campello, Cláudio Afonso Pinho, Lopes, José Ricardo, de Figueiredo, Lúcia Daniel Machado, da Silva   +9 more
openaire   +2 more sources

Preserving Fertility in Young Women: Triple‐Step Strategy for Managing Giant Endometriomas With Minimal AMH Decline—A Case Report

Case Reports in Obstetrics and Gynecology, Volume 2026, Issue 1, 2026.
Endometriomas are a frequent cause of infertility in reproductive‐aged women, often requiring surgery. However, cystectomy for large endometriomas may reduce ovarian reserve, as indicated by decreased anti‐Müllerian hormone (AMH) levels. This case report presents a triple‐step approach to managing a 20‐year‐old woman with bilateral endometriomas and ...
Arry Soryadharma, Hanom Husni Syam, Mulyanusa Amarullah Ritonga, Suraiya Saleem   +3 more
wiley   +1 more source

Cytomolecular and In Vitro Toxicity Studies on Bisphenol A Effect on Ovine Granulosa Cells

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Bisphenol A (BPA), an organic environment chemical, has extensive presence in consumer goods and food/feed items. The present study aimed to explore how BPA influenced the viability, proliferation, apoptosis, and steroidogenic activity of ovine ovarian granulosa cells (GCs).
Poonam Kumari Singh, Bogapathi Sampath Kumar, Sumanta Nandi, Paluru Subramniyam Parameswara Gupta, Sukanta Mondal, Imtiaz Rabbani   +5 more
wiley   +1 more source

In Vitro Gamete Production in Mammals: Decades of Pioneering Approaches in Germ Cell and Stem Cell Biology Supporting Innovative Discovery and Expansion of Human Reproductive Potential

Molecular Reproduction and Development, Volume 92, Issue 12, December 2025.
ABSTRACT During recent decades a myriad of approaches have emerged for generating surrogate gametes or achieving in vitro gametogenesis (IVG). The most recent approaches to IVG include the development of increasingly complex culture systems, use of companion cells combined with germ line cells in two‐ or three‐dimensional configurations, derivation of ...
Keith E. Latham
wiley   +1 more source