SET protein up-regulated testosterone production in the cultured preantral follicles
Background We found previously that the expression of SET gene was up-regulated in polycystic ovaries. Evidences suggested that SET protein was essential for regulating both the promoter activity of CYP17A1 and the biological activity of P450c17. In this
Xu Boqun +9 more
doaj +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Morphological Study of Isolated Ovarian Preantral Follicles Using Fibrin Gel Plus Platelet Lysate after Subcutaneous Transplantation [PDF]
Objective: Ovarian and follicle transplantation may preserve fertility in young cancer survivors. In this study, we have transplanted preantral follicles using fibrin gel as a carrier and fibrin gel supplemented with platelet lysate (PL) as a rich ...
Ali Reza Rajabzadeh +4 more
doaj
Bioengineering Supports Preantral Follicle In Vitro Growth
ecent advances using bioengineering methods (e.g. biomaterials, 3D-printing, microfluidics tec.) has opened the possibility to study female reproductive system and reproductive diseases in a totally new way and with unpredictable ...
openaire +1 more source
Chamomile contains different bioactive agents such as flavonoids and phytosterols with potential anti‐inflammatory, antioxidant, analgesic, antispasmodic, and antitumor characteristics. According to our findings, animal studies have demonstrated the potential benefits of Chamomile consumption in the treatment of PCOS. In contrast, human studies yielded
Zahra Firoozi +3 more
wiley +1 more source
Inhibin A and B secretion in mouse preantral follicle culture [PDF]
Conditioned media from single mouse ovarian follicles cultured from the early preantral stage up to complete maturity were analysed for different immunoreactive inhibin forms. The inhibin assays measured (i) alpha-specific inhibin, as represented by a mix of 32 and and 57 kDa inhibins, inhibin precursors, alpha-subunit and its precursors; (ii) dimeric ...
Smitz, Johan, Cortvrindt, R.
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Zinc Deficiency Disrupts Germ Cell Nest Breakdown During In Vitro Ovary Culture
ABSTRACT In mammals, the size of the non‐renewable primordial follicle pool is established before or soon after birth. Primordial follicles, each composed of a single oocyte surrounded by somatic cells, are the only source of gametes during the entire reproductive lifespan of the female.
James M. Hester +3 more
wiley +1 more source
Ovarian features in white-tailed deer (Odocoileus virginianus) fawns and does.
The knowledge about ovarian reserve is essential to determine the reproductive potential and to improve the methods of fertility control for overpopulated species, such as white-tailed deer (Odocoileus virginianus). The goal of this study was to evaluate
G D A Gastal +8 more
doaj +1 more source
Simulated Microgravity Using a Rotary Culture System Compromises the In Vitro Development of Mouse Preantral Follicles. [PDF]
Growing cells in simulated weightlessness condition might be a highly promising new technique to maintain or generate tissue constructs in a scaffold-free manner.
Shen Zhang +7 more
doaj +1 more source
Isolation and characterization of preantral follicles from foetal bovine ovaries [PDF]
A simple, mechanical method is described for the isolation of preantral follicles from bovine foetuses of 220-280 days of gestation. On average, 2918 + 621 (s.d.) preantral follicles were isolated per ovary. The isolated preantral follicles were characterized on the basis of the morphological appearance of the surrounding granulosa cells, the number of
Hulshof, S. C. J. +4 more
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