Results 61 to 70 of about 9,462 (214)

A New Diagnostic Strategy for Polycystic Ovary Syndrome Combining Japanese and International Diagnostic Criteria Using Anti‐Müllerian Hormone

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim We had defined the anti‐Müllerian hormone (AMH) cut‐off value level 2 aligned with the Rotterdam/International Evidence‐based Guideline (IEBG) for the Assessment and Management of polycystic ovary syndrome (PCOS) 2023 criteria. In this study, we evaluated the utility of AMH cut‐off value level 2 in patients who could not be diagnosed under
Hiroki Noguchi, Takeshi Iwasa, Akira Iwase, Haruhiko Kanasaki, Fuminori Kimura, Koji Kugu, Kazuki Saito, Tsuyoshi Baba, Tetsuaki Hara, Toshiya Matsuzaki   +9 more
wiley   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

A protocol to isolate and qualify purified human preantral follicles in cases of acute leukemia, for future clinical applications

Journal of Ovarian Research, 2018
Background Autotransplantation of cryopreserved ovarian cortex can be associated with a risk of cancer cell reseeding. This issue could be eliminated by grafting isolated preantral follicles. Collagenase NB6 is an enzyme produced under good manufacturing
Elodie Mouloungui, Tristan Zver, Christophe Roux, Clotilde Amiot   +3 more
doaj   +1 more source

Regulation of ovarian function: the role of anti-Mullerian hormone [PDF]

, 2002
Anti-Mullerian hormone (AMH), also known as Mullerian inhibiting substance, is a member of the transforming growth factor beta superfamily of growth and differentiation factors.
Durlinger, A.L.L. (Alexandra), Themmen, A.P.N. (Axel), Visser, J.A. (Jenny)   +2 more
core   +2 more sources

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

SET protein up-regulated testosterone production in the cultured preantral follicles

Reproductive Biology and Endocrinology, 2013
Background We found previously that the expression of SET gene was up-regulated in polycystic ovaries. Evidences suggested that SET protein was essential for regulating both the promoter activity of CYP17A1 and the biological activity of P450c17. In this
Xu Boqun, Gao Lingling, Cui Yugui, Gao Li, Dai Xue, Li Mei, Zhang Yuan, Ma Xiang, Diao Feiyang, Liu Jiayin   +9 more
doaj   +1 more source

Oxygen Hyperbaric Exposure Induces GLUT4 Expression Reduction and No Folliculogenesis Alterations in Rat PCOS with Insulin Resistance Model [PDF]

, 2015
Objectives: To know effect of hyperbaric oxygen therapy to GLUT4 expression and folliculogenesis in rat PCOS with insulin resistent model.Materials and Methods: this is an analytic experimental study used 30 rats induced by testosterone propionate ...
Santoso, B. (Budi), Veterini, V. (Varianida), Widjiati, W. (Widjiati)   +2 more
core   +2 more sources

Salidroside Ameliorates Polycystic Ovary Syndrome in Mice by Regulating the AKT/NF‐κB/NLRP3‐HAS2 Axis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Salidroside ameliorates PCOS via inhibiting the ROS‐AKT/NF‐κB axis and suppressing NLRP3 inflammasome activation. It disrupts the NLRP3–LAP‐TGFβ1 interaction to block TGF‐β‐SMAD2/3 signaling and consequent ovarian fibrosis. Together with hyaluronan synthase 2 (HAS2) downregulation, these effects alleviate inflammation and hyaluronan overaccumulation ...
Jing‐hang Li, Shu‐Ming Shi, Li‐Ying Liu, Yu‐Yan He, Guan‐Lin Jia, Lin‐Yi Qu, Zhi‐Chao Chi, Jia‐hui Leng, Hong‐jie Xu, Tian Lan, Dong‐lei Yan, Il‐keun Kong, Xian‐Feng Yu, Ming‐Jun Zhang, Yong‐Xun Jin   +14 more
wiley   +1 more source

Morphological Study of Isolated Ovarian Preantral Follicles Using Fibrin Gel Plus Platelet Lysate after Subcutaneous Transplantation [PDF]

Cell Journal, 2015
Objective: Ovarian and follicle transplantation may preserve fertility in young cancer survivors. In this study, we have transplanted preantral follicles using fibrin gel as a carrier and fibrin gel supplemented with platelet lysate (PL) as a rich ...
Ali Reza Rajabzadeh, Hossein Eimani, Homa Mohseni Koochesfahani, Abdol-Hossein Shahvardi, Rouhollah Fathi   +4 more
doaj  

Preservation of bovine preantral follicle viability and ultra-structure after cooling and freezing of ovarian tissue [PDF]

, 2008
Bovine preantral follicles within ovarian fragments were exposed and cryopreserved in absence or presence of 1.5 M glycerol (GLY), ethylene glycol (EG), propanediol (PROH) or dimethyl sulfoxide (DMSO), undergoing a previous cooling at 20 °C for 1 h ...
Báo, Sônia Nair, Celestino, Juliana Jales de Hollanda, Figueiredo, José Ricardo de, Lopes, Cláudio Afonso Pinho, Martins, Fabrício Sousa, Matos, Maria Helena Tavares, Melo, Mônica Aline Parente, Rodrigues, Ana Paula Ribeiro, Santos, Regiane Rodrigues dos, Silva, José Roberto Viana   +9 more
core   +1 more source