Results 241 to 250 of about 98,126 (343)

Delayed Loop Ileostomy Reversal Increases the Risk of Colitis and Clostridium difficile Infection

ANZ Journal of Surgery, EarlyView.
Delayed loop ileostomy reversal is associated with increased post‐operative complications specifically colitis and Clostridium difficile colitis. The COVID‐19 pandemic caused a significant delay in ileostomy reversal timing. ABSTRACT Background Temporary loop ileostomy formation is a routine procedure performed to protect distal colorectal anastomosis.
Yan S. Tan, S. Fujino, Marcus E. H. Chan, Johann W. Z. Leh, Asiri M. K. Arachchi, V. Narasimhan, Thomas S. Suhardja, Hanumant S. Chouhan, Pathirajage C. K. Saranasuriya, James T. Lim, Thang C. Nguyen, William M. K. Teoh, Yeng K. Tay   +12 more
wiley   +1 more source

Feeding the gut-immune axis: dietary, prebiotic, and probiotic strategies to target persistent inflammation in ART-treated HIV: a narrative review. [PDF]

Front Immunol
Fletcher AA, Koberssy Z, Daher J, Moussallem N, McComsey GA.   +4 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy. [PDF]

Life (Basel)
Kahana A.
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Effect of Inulin-Type Fructans on Body Composition, Carbohydrate Metabolism and Energy Expenditure in Patients with Psoriasis: Results of INGUTSKIN Randomized Controlled Trial. [PDF]

Nutrients
Bieglecka K, Kęszycka PK, Czerwińska J, Pastuszak K, Lange E, Owczarczyk-Saczonek A, Krupa-Kozak U.   +6 more
europepmc   +1 more source

Oral Butyrate Reduces Progression of Kidney Damage in an L‐NAME‐Induced Diabetic Kidney Disease Mouse Model

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetic kidney disease (DKD) is one of the main causes of kidney failure worldwide. Interestingly, patients affected by DKD are characterised by a low abundance of gut bacteria producing short fatty acids including butyrate, which is suggested to play a role in the decline of renal function.
Maria Novella Nicese, Angela Koudijs, Reshma Lalai, Cristina Avramut, Rico J. E. Derks, Elena Sánchez‐López, Martin Giera, Amanda C. M. Pronk, Artemiy Kovynev, Sander Kooijman, Patrick C. N. Rensen, Roel Bijkerk, Bernard M. van den Berg, Joris I. Rotmans   +13 more
wiley   +1 more source

Prebiotic intervention changes host and microbe proteomes in plasma extracellular vesicles of Parkinson's disease. [PDF]

Sci Rep
Sharma D, Voigt RM, Hall DA, Cantu-Jungles TM, Shaikh M, Engen PA, Jones J, Li S, Hamaker BR, Forsyth CB, Bishehsari F, de Menezes EGM, Norris PJ, Goetz CG, Keshavarzian A.   +14 more
europepmc   +1 more source

First‐In‐Human Study of Mirogabalin (BM2216) Sustained‐Release Tablets: Safety, Tolerability, Pharmacokinetics, Food Effect and Dose Proportionality With Comparison to Mirogabalin Besylate in Healthy Participants

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To characterise the pharmacokinetics (PKs) and safety of BM2216 sustained‐release (SR) tablets after single‐dose oral administration under fasted/fed conditions in healthy participants, assess the effect of food and dose proportionality, and compare the single and multiple‐dose PK of BM2216 SR tablets with mirogabalin besylate tablets to ...
Peiyang Song, Hongtao Zhao, Mingxue Zhu, Lei Wan, Yuan Chen, Zhongping Li, Chengyong Tang   +6 more
wiley   +1 more source

Mushroom-Derived Phenolic Compounds as Emerging Prebiotic-like Modulators of Gut Microbiota, Intestinal Health, and Metabolism. [PDF]

Pharmaceuticals (Basel)
Garcia J, Olo-Fontinha E, Silva J, Dias-Costa R, Alves MJ, Gouvinhas I.   +5 more
europepmc   +1 more source