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The origin of life is in a sense a genetic problem, for, as H. J. Muller pointed out many years ago, the essential attribute that identifies living matter is its capacity to replicate itself and its variants (1). Because this uniquely biological property
Horowitz, N. H., Hubbard, Jerry S.
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Background Our current understanding of evolution is so tightly linked to template-dependent replication of DNA and RNA molecules that the old idea from Oparin of a self-reproducing 'garbage bag' ('coacervate') of chemicals that predated fully-fledged ...
Vasas Vera +4 more
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Parasites Sustain and Enhance RNA-Like Replicators through Spatial Self-Organisation. [PDF]
In a prebiotic RNA world, parasitic behaviour may be favoured because template dependent replication happens in trans, thus being altruistic. Spatially extended systems are known to reduce harmful effects of parasites. Here we present a spatial system to
Enrico Sandro Colizzi, Paulien Hogeweg
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Origin of symbol-using systems: speech, but not sign, without the semantic urge [PDF]
Natural language—spoken and signed—is a multichannel phenomenon, involving facial and body expression, and voice and visual intonation that is often used in the service of a social urge to communicate meaning.
Alberts B +27 more
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Prebiotic Reaction Networks in Water
A prevailing strategy in origins of life studies is to explore how chemistry constrained by hypothetical prebiotic conditions could have led to molecules and system level processes proposed to be important for life’s beginnings. This strategy has yielded
Quoc Phuong Tran +2 more
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Modern views of ancient metabolic networks [PDF]
Metabolism is a molecular, cellular, ecological and planetary phenomenon, whose fundamental principles are likely at the heart of what makes living matter different from inanimate one. Systems biology approaches developed for the quantitative analysis of
Goldford, Joshua E., Segrè, Daniel
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Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss +2 more
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Thresholds in Origin of Life Scenarios
Summary: Thresholds are widespread in origin of life scenarios, from the emergence of chirality, to the appearance of vesicles, of autocatalysis, all the way up to Darwinian evolution.
Cyrille Jeancolas +2 more
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Prebiotic chemical origin of biomolecular complementarity
The early Earth, devoid of the protective stratospheric ozone layer, must have sustained an ambient prebiotic physicochemical medium intensified by the co-existence of shortwave UV photons and very low energy electrons (vLEEs).
Y. Sajeev
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Prebiotic Homochirality as a Critical Phenomenon
The development of prebiotic homochirality on early-Earth or another planetary platform may be viewed as a critical phenomenon. It is shown, in the context of spatio-temporal polymerization reaction networks, that environmental effects -- be them ...
A Brandenburg +18 more
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