Results 21 to 30 of about 19,936 (198)

The Origin of Life [PDF]

open access: yes, 1974
The origin of life is in a sense a genetic problem, for, as H. J. Muller pointed out many years ago, the essential attribute that identifies living matter is its capacity to replicate itself and its variants (1). Because this uniquely biological property
Horowitz, N. H., Hubbard, Jerry S.
core   +1 more source

Evolution before genes

open access: yesBiology Direct, 2012
Background Our current understanding of evolution is so tightly linked to template-dependent replication of DNA and RNA molecules that the old idea from Oparin of a self-reproducing 'garbage bag' ('coacervate') of chemicals that predated fully-fledged ...
Vasas Vera   +4 more
doaj   +1 more source

Parasites Sustain and Enhance RNA-Like Replicators through Spatial Self-Organisation. [PDF]

open access: yesPLoS Computational Biology, 2016
In a prebiotic RNA world, parasitic behaviour may be favoured because template dependent replication happens in trans, thus being altruistic. Spatially extended systems are known to reduce harmful effects of parasites. Here we present a spatial system to
Enrico Sandro Colizzi, Paulien Hogeweg
doaj   +1 more source

Origin of symbol-using systems: speech, but not sign, without the semantic urge [PDF]

open access: yes, 2014
Natural language—spoken and signed—is a multichannel phenomenon, involving facial and body expression, and voice and visual intonation that is often used in the service of a social urge to communicate meaning.
Alberts B   +27 more
core   +2 more sources

Prebiotic Reaction Networks in Water

open access: yesLife, 2020
A prevailing strategy in origins of life studies is to explore how chemistry constrained by hypothetical prebiotic conditions could have led to molecules and system level processes proposed to be important for life’s beginnings. This strategy has yielded
Quoc Phuong Tran   +2 more
doaj   +1 more source

Modern views of ancient metabolic networks [PDF]

open access: yes, 2018
Metabolism is a molecular, cellular, ecological and planetary phenomenon, whose fundamental principles are likely at the heart of what makes living matter different from inanimate one. Systems biology approaches developed for the quantitative analysis of
Goldford, Joshua E., Segrè, Daniel
core   +1 more source

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

open access: yesBeilstein Journal of Organic Chemistry, 2017
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss   +2 more
doaj   +1 more source

Thresholds in Origin of Life Scenarios

open access: yesiScience, 2020
Summary: Thresholds are widespread in origin of life scenarios, from the emergence of chirality, to the appearance of vesicles, of autocatalysis, all the way up to Darwinian evolution.
Cyrille Jeancolas   +2 more
doaj   +1 more source

Prebiotic chemical origin of biomolecular complementarity

open access: yesCommunications Chemistry, 2023
The early Earth, devoid of the protective stratospheric ozone layer, must have sustained an ambient prebiotic physicochemical medium intensified by the co-existence of shortwave UV photons and very low energy electrons (vLEEs).
Y. Sajeev
doaj   +1 more source

Prebiotic Homochirality as a Critical Phenomenon

open access: yes, 2005
The development of prebiotic homochirality on early-Earth or another planetary platform may be viewed as a critical phenomenon. It is shown, in the context of spatio-temporal polymerization reaction networks, that environmental effects -- be them ...
A Brandenburg   +18 more
core   +2 more sources

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