Results 101 to 110 of about 31,572 (245)

Head‐to‐head comparison of the diagnostic value of fecal and serum carcinoembryonic antigen for colorectal cancer detection

International Journal of Cancer, Volume 159, Issue 2, Page 516-525, 15 July 2026.
What's new? The diagnostic value of fecal versus serum carcinoembryonic antigen (CEA) for colorectal cancer detection remains unclear. This study provides a head‐to‐head comparison of serum and fecal CEA using matched samples from two large colorectal cancer screening studies and two fecal sample processing methods.
Xianzhe Li, Zitong Zhao, Lara Stassen, Anjana Pradeep Maya, Megha Bhardwaj, Teresa Seum, Janhavi R. Raut, Tafirenyika Gwenzi, Michael Hoffmeister, Petra Schrotz‐King, Hermann Brenner   +10 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Oxidative Stress Induced Senescent Macrophage‐Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming

Aging Cell, Volume 25, Issue 7, July 2026.
Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang, Jingtian Mu, Wei Zhao, Can Hu, Xueke Shi, Hongmei Zhou, Junjiang Liu, Fanglong Wu   +7 more
wiley   +1 more source

Predictive factors for the absence of high‐grade intraepithelial lesions in LLETZ specimens following a prior histological diagnosis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 7, Page 1240-1246, July 2026.
About 9.4% of patients with biopsy‐proven high‐grade cervical lesions had ultimately no high‐grade lesion (HGIL) in the excision specimen. The probability of the absence of HGIL was significantly increased in patients with a small lesion, with minor changes or normal colposcopy, and in those with normal cytology or minor abnormalities.
Sophia Assirlikian, Julien Mancini, Charles‐André Philip, Geoffroy Canlorbe, Henri Azaïs, Eva Fuss‐Blanco, Lise Lecointre, Karine Le Bail Carval, Dave Nkounawa, Andriniaina Ravelojaona, Xavier Carcopino   +10 more
wiley   +1 more source

Comprehensive analysis of liver and blood miRNA in precancerous conditions. [PDF]

Sci Rep, 2020
Umezu T, Tsuneyama K, Kanekura K, Hayakawa M, Tanahashi T, Kawano M, Taguchi YH, Toyoda H, Tamori A, Kuroda M, Murakami Y.   +10 more
europepmc   +1 more source

The Taboo of Withdrawal: Firsthand Perspectives From Former Doctoral Candidates in Poland and Portugal

Higher Education Quarterly, Volume 80, Issue 3, July 2026.
ABSTRACT In knowledge‐based societies, withdrawal from doctoral education is often seen and spoken about as embarrassing, undesirable, and awkward. Emerging from complex conditions—a mix of profoundly personal factors and weighty contextual factors—withdrawal tends to be a silenced or shamed process, producing a layered dynamic of taboo upon taboo upon
Patrícia Alves, Marta Kowalczuk‐Walędziak, Amélia Lopes, Izabela Krasnicka, Isabel Menezes   +4 more
wiley   +1 more source

Educational inequalities in cervical cancer mortality in the Baltic countries and Finland in the context of organized screening: A register‐based study 2000–2015

International Journal of Cancer, Volume 158, Issue 12, Page 3132-3140, 15 June 2026.
What's new? This study shows that absolute and relative educational inequalities in cervical cancer mortality are much larger in the Baltic countries than in Finland, where an organized screening programme was introduced more than 40 years earlier. After the introduction of organized screening, cervical cancer mortality declined among low‐educated ...
Oskar Nõmm, Kaire Innos, Domantas Jasilionis, Juris Krumins, Pekka Martikainen, Kersti Pärna, Andrew Stickley, Mall Leinsalu   +7 more
wiley   +1 more source

Cost‐effectiveness analysis of human papillomavirus (HPV) genotyping strategies for management of HPV‐positive women in cervical cancer screening

International Journal of Cancer, Volume 158, Issue 12, Page 3141-3151, 15 June 2026.
What's new? Persistent infection with high‐risk human papillomavirus (HPV) causes most invasive cervical cancer cases, leading many countries to transition from cytology to primary HPV‐based screening. Despite the benefits, HPV‐based screening may also lead to unnecessary procedures, psychological burden, and strain on healthcare systems.
Kelsi R. Kroon, Johannes A. Bogaards, Johannes Berkhof   +2 more
wiley   +1 more source

Precancerous Condition [PDF]

, 2020
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source