Results 81 to 90 of about 31,685 (237)

A Novel Blood‐Based Screening Test for Colorectal Cancer Using Raman Spectroscopy

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Label‐free vibrational spectroscopic techniques (Raman spectroscopy) combined with machine learning (ML) methodologies have huge potential for the development of screening and diagnostic tests in oncology. Traditionally, screening for colorectal cancer (CRC) has relied on immunochemical faecal occult blood (iFOBT) testing; however ...
Jett Karolewski, Georgia Carroll, Rosemary Carroll, Rodney J. Scott, Stephen Smith, Joel Petit   +5 more
wiley   +1 more source

Loss to follow‐up in patients diagnosed with or treated for low‐ and high‐grade squamous intraepithelial lesions: A comparison of general practitioner‐ and gynecologist‐led surveillance

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Follow‐up by general practitioners after LSIL or treated HSIL was associated with higher loss to follow‐up rates compared with gynecologist‐led care. Loss to follow‐up was 38.1% versus 16.6% for LSIL at 12 months and 44.3% versus 24.1% for treated HSIL at 24 months.
Lieke van de Kam, Albert Siebers, Ruud Bekkers, Dennis van Hamont, Jurgen Piek   +4 more
wiley   +1 more source

Bladder washing cytology in the initial evaluation of patients with neuro‐urological disorders: to do or not to do?

BJU International, EarlyView.
Objectives To evaluate if bladder washing cytology (BWC) provides a diagnostic benefit in the initial evaluation of patients with neuro‐urological disorders. Patients and Methods This prospective cross‐sectional study investigated a consecutive series of patients with lower urinary tract symptoms referred for neuro‐urological evaluation at our ...
Fabienne Lehner, Sarah Dugas, Veronika Birkhäuser, Oliver Gross, Lorenz Leitner, Ulrich Mehnert, Lara Stächele, Collene E. Anderson, Thomas M. Kessler   +8 more
wiley   +1 more source

Gastric epithelial histology and precancerous conditions. [PDF]

World J Gastrointest Oncol, 2022
Yang H, Yang WJ, Hu B.
europepmc   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source

Insights into the Role of Matrix Metalloproteinases in Precancerous Conditions and in Colorectal Cancer. [PDF]

Cancers (Basel), 2021
Pezeshkian Z, Nobili S, Peyravian N, Shojaee B, Nazari H, Soleimani H, Asadzadeh-Aghdaei H, Ashrafian Bonab M, Nazemalhosseini-Mojarad E, Mini E.   +9 more
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Current positions regarding the diagnosis and screening of colorectal cancer and precancerous changes of bowel. Analysis of clinical cases

Gastroenterologìa
The article deals with the problem of colorectal cancer and precancerous changes of bowel. Risk factors, clinical symptoms, diagnostic methods, directions for the prevention of colorectal cancer and precancer are considered.
Yu.M. Stepanov, O.M. Vlasova, I.Y. Budzak   +2 more
doaj   +1 more source

Use of folic acid supplementation to halt and even reverse the progression of gastric precancerous conditions: a meta-analysis. [PDF]

BMC Gastroenterol, 2022
Lei J, Ren F, Li W, Guo X, Liu Q, Gao H, Pang Y, He Y, Guo J, Zeng J.   +9 more
europepmc   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source