Results 61 to 70 of about 31,572 (245)

Validated, Reliable, and Novel Skin Frailty Scale for Outpatient Usage and Its Association With Age, Sex, and Non‐Melanoma Skin Cancer: An Observational Study

JEADV Clinical Practice, EarlyView.
Skin frailty (SF) is a common condition affecting adults aged ≥65 years. However, the lack of a validated and reliable visual scale to assess SF severity is a barrier to clinical care and research. In this study, we developed a 9‐parameter Skin Frailty Score (SFS), validated by two board‐certified dermatologists and meeting item and scale level content
Po‐Han Ho, Farah Abou‐Taleb, Shufeng Li, Kiana Yekrang, Vijaytha Muralidharan, Pirunthan Pathmarajah, Sophia Katherine Longo, Zakia Rahman, Albert Sean Chiou, Anne Lynn S. Chang   +9 more
wiley   +1 more source

Microbial Dysbiosis in Oral Squamous Cell Carcinoma (OSCC) and Oral Potentially Malignant Disorders: A Systematic Review

Journal of Indian Academy of Oral Medicine and Radiology
Background: Oral squamous cell carcinoma (OSCC) is a highly prevalent malignancy with increasing global incidence. Oral potentially malignant disorders (OPMDs), often precede OSCC. Emerging evidence suggests that oral microbial dysbiosis (OMD) may play a
Kandasamy Murugan, Kesavaram Padmavathy, Ravi Jayasrikrupaa, Loganathan Kopperundevi   +3 more
doaj   +1 more source

Prevalence of precancerous and cancerous cervical lesions in women from Batna, Algeria [PDF]

Epidemiology and Health System Journal
Background and aims: Cervical cancer is the fourth most frequently diagnosed cancer among Algerian women and the seventh in Batna. This study sought to evaluate the prevalence of precancerous and cancerous cervical lesions and identify the target age ...
Waffa Bouafia, Abdelmoudjib Ghecham, Rachid Benslitane   +2 more
doaj   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

Med Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang, Chenchen Wang, Tianliang Liu, Ziliang Wang, Zhe Zhang   +4 more
wiley   +1 more source

Opportunistic screening protocols for cervical carcinoma among different female populations in Chongqing

Di-san junyi daxue xuebao, 2019
Objective To evaluate the 5 protocols of opportunistic screening for cervical carcinoma among different female populations, in order to explore optional protocol for the women with different clinical characteristics.
YAN Li, YANG Jun, ZHOU Deping, ZHOU Xiaojun   +3 more
doaj   +1 more source

Development and Validation of a Questionnaire‐Based Model for Households With Multiple Helicobacter pylori Infections: A Family‐Based Screening Strategy

Med Research, EarlyView.
This study developed and externally validated a questionnaire‐based household risk model to identify families with multiple Helicobacter pylori infections. Using only noninvasive, readily available household information, the model showed good discrimination and enabled a family‐based screening strategy that substantially improved detection efficiency ...
Yifan Qiu, Xianzhu Zhou, Yi Hu, Liting Shen, Jiayue Wang, Shihan Xu, Huiyun Zhu, Huabing Huang, Zhaoshen Li, Yiqi Du   +9 more
wiley   +1 more source

Current positions regarding the diagnosis and screening of colorectal cancer and precancerous changes of bowel. Analysis of clinical cases

Gastroenterologìa
The article deals with the problem of colorectal cancer and precancerous changes of bowel. Risk factors, clinical symptoms, diagnostic methods, directions for the prevention of colorectal cancer and precancer are considered.
Yu.M. Stepanov, O.M. Vlasova, I.Y. Budzak   +2 more
doaj   +1 more source

Endoscopic Submucosal Dissection for Gastrointestinal Superficial Lesions: Initial Experience in a Single Portuguese Center

GE: Portuguese Journal of Gastroenterology, 2015
Introduction: Endoscopic submucosal dissection (ESD) is a minimally invasive organ-sparing endoscopic technique which allows en bloc resection of premalignant and early malignant lesions of the gastrointestinal tract regardless of size.
José Rodrigues, Joana Carmo, Liliana Carvalho, Pedro Barreiro, Cristina Chagas   +4 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source