Results 51 to 60 of about 31,685 (237)

Current Concepts of Precancerous Lesions of Hepatocellular Carcinoma: Recent Progress in Diagnosis

Diagnostics, 2023
The most common cause of hepatocellular carcinoma (HCC) is chronic hepatitis and cirrhosis. It is proposed that precancerous lesions of HCC include all stages of the disease, from dysplastic foci (DF), and dysplastic nodule (DN), to early HCC (eHCC) and ...
Ziyue Liao, Cuiping Tang, Rui Luo, Xiling Gu, Jun Zhou, Jian Gao   +5 more
doaj   +1 more source

Resource‐Adapted Triage Strategies for Women Testing HPV Positive With Self‐Collected Vaginal Samples in Cameroon

International Journal of Cancer, EarlyView.
Although human papillomavirus (HPV) testing is recommended for cervical cancer screening in low‐ and middle‐income countries, optimal management of HPV‐positive women remains undetermined, particularly in resource‐limited settings. Here, using data from the 3T study involving women in Cameroon, the authors evaluated the ability of extended HPV ...
Micol Murtas, Pierre Vassilakos, Ania Wisniak, Ketty Hu, Marc Arbyn, Gilles W. Tankeu Happi, Esther Abatsong, François Marcel Ndam Nsangou, Jean‐Christophe Tille, Essia Saiji, Bruno Kenfack, Patrick Petignat   +11 more
wiley   +1 more source

Validity of Serum Pepsinogen I/II Ratio for the Diagnosis of Gastric Epithelial Dysplasia and Intestinal Metaplasia during the Follow-Up of Patients at Risk for Intestinal-Type Gastric Adenocarcinoma

Neoplasia: An International Journal for Oncology Research, 2004
A cohort of individuals (n = 136) with lesions as severe as atrophic chronic gastritis (ACG) was cross-sectionally evaluated for the validity assessment of pepsinogen I (PGI) and pepsinogen II (PGII) serum levels for the diagnosis of intestinal ...
Mário Dinis-Ribeiro, Altamiro da Costa-Pereira, Carlos Lopes, Joana Barbosa, Mateus Guilherme, Luís Moreira-Dias, Helena Lomba-Viana, Rui Silva, Nuno Abreu, Rafael Lomba-Viana   +9 more
doaj   +1 more source

Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort

International Journal of Cancer, EarlyView.
The immune system has been implicated as a major driver in pancreatic cancer etiology. Previous cohort studies have found associations between pancreatic cancer and single immune system‐derived markers, but omics‐based evidence remains scarce. In this prospective case–control study, the authors investigated 92 proteins involved in immune reactions and ...
Verena A. Katzke, Yue Chen, Srimanti Dutta, Federico Canzian, Julie Louise Munk Andersen, Agnetha Linn Rostgaard‐Hansen, Léa Bouteille, Vinciane Rebours, Thérèse Truong, Matthias B. Schulze, Benedetta Bendinelli, Valeria Pala, Vittorio Simeon, Rosario Tumino, Carlotta Sacerdote, Roel Vermeulen, P. Martijn Kolijn, Sjoerd G. Elias, Marta Crous‐Bou, Maria‐José Sánchez, Ana Jimenez‐Zabala, José María Huerta, Marcela Guevara, Nick Wareham, Marie Breeur, Mattias Johansson, James Yarmolinsky, Daniele Campa, Rudolf Kaaks   +28 more
wiley   +1 more source

An experience of oral cancer screening in the workplace: a cross-sectional study [PDF]

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Objectives: Oral cancer is a serious disease whose prognosis worsens greatly with late detection and diagnosis. Therefore, a demand is pressing for a cost-effective model that is optimal for mass screening for oral cancer.
Ayat Gamal-AbdelNaser, Mohamed Tariq Mohamed, Aya Mohamed Ahmed, Marina Ezzat Nabeh, Mostafa Abdallah Anis, Mahmoud Mohammed AbdelAziz   +5 more
doaj   +1 more source

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

HPV Testing Versus Cytology for Cervical Cancer Screening Among Women 50 Years and Older: Evidence From the HPV FOCAL Randomized Controlled Trial

International Journal of Cancer, EarlyView.
ABSTRACT Evidence on the comparative effectiveness of HPV testing versus cytology specifically in women aged ≥ 50 years who are approaching screening cessation remains limited. This analysis included 6471 women aged ≥ 50 at baseline screening in the HPV FOCAL randomized clinical trial. Women were randomly allocated to receive cytology (Control Group, n 
Md Saiful Alam, Laurie W. Smith, Lovedeep Gondara, Darrel Cook, Ruth Elwood Martin, Stuart Peacock, Lily Proctor, Gavin Stuart, David Patrick, Eduardo L. Franco, Mel Krajden, Anna Gottschlich, Gina S. Ogilvie   +12 more
wiley   +1 more source

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

International Journal of Cancer, EarlyView.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li, Elaheh Zarean, Danmeng Lily Li, Yiyue Zhu, Shuai Li, Enes Makalic, Catriona McLean, Graham G. Giles, Roger L. Milne, Melissa C. Southey, Pierre‐Antoine Dugué   +10 more
wiley   +1 more source

Prevalence of precancerous and cancerous cervical lesions in women from Batna, Algeria [PDF]

Epidemiology and Health System Journal
Background and aims: Cervical cancer is the fourth most frequently diagnosed cancer among Algerian women and the seventh in Batna. This study sought to evaluate the prevalence of precancerous and cancerous cervical lesions and identify the target age ...
Waffa Bouafia, Abdelmoudjib Ghecham, Rachid Benslitane   +2 more
doaj   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source