Results 111 to 120 of about 8,350,584 (283)

Flexible Cervical Photodynamic Therapy Device

open access: yesTranslational Biophotonics, EarlyView.
This paper aims to design a flexible photodynamic therapy device for the cervix and cervical vault, using an LED array, light guide, and flexible trumpet‐shaped homogenizer. Simulations and tests show output irradiance up to 98 mW/cm2 with < 14.2% variation, offering a low‐cost solution for cervical cancer and precancerous lesions.
Teng Jin   +5 more
wiley   +1 more source

CEA Levels in Gastric Juice in Precancerous Conditions and Cancer

open access: yesThe International Journal of Biological Markers, 1987
First described in 1965 as a specific antigen for cancer of the colon, CEA is now considered to be an antigen associated with many types of malignant neoplasia, although the CEA-Test's role in clinical routine has yet to be clearly defined. In the present study CEA levels in gastric juice were measured in subjects with gastric carcinoma (n = 25) and ...
Ronchi A   +8 more
openaire   +3 more sources

Effectiveness of Gastric Cancer Endoscopic Screening in Intermediate‐Risk Countries—A Systematic Review and Meta‐Analysis

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Gastric cancer remains a major cause of cancer‐related mortality in intermediate‐risk countries. Although endoscopic screening is widely implemented in high‐risk regions, its effectiveness and economic viability in intermediate‐risk settings remain uncertain.
M. B. Mourato   +6 more
wiley   +1 more source

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

"Catch them before it becomes too late"-oral cancer detection. Report of two cases and review of diagnostic AIDS in cancer detection

open access: yesInternational Journal of Preventive Medicine, 2012
Most oral and oropharyngeal squamous cell carcinomas (OOSCCs) are in advanced stages at diagnosis, and treatment does not improve survival rates. Early recognition and diagnosis of OOSCCs might improve patient survival and reduce treatment-related ...
Payal Garg, Freny Karjodkar
doaj  

hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

open access: yesAging Cell, EarlyView.
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam   +15 more
wiley   +1 more source

Pap smear in Early Detection of Cervical Precancerous Lesions in Erbil

open access: yesAdvanced Medical Journal
Background and objectives: Cervical cancer remains common. This may be because Iraq has no cervical cancer screening or human papilloma virus vaccination program.
Avin Wlya Muhammad, Haitham Issa Bahoo
doaj   +1 more source

Epigenetically‐Upregulated CD98 Shed Light on the Precancerous Diagnosis and Prognosis Prediction of Esophageal Cancer

open access: yesCancer Science, EarlyView.
This study confirmed that hypomethylation‐induced upregulation of CD98 promoted ESCC cell proliferation by regulating the cell cycle and was correlated with poorer overall survival of ESCC patients. Combined panels of immunohistochemistry (CD98 and P53) are recommended for accurate diagnosis of esophageal precancerous lesions.
Xue Zhang   +13 more
wiley   +1 more source

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