A tug-of-war between driver and passenger mutations in cancer and other adaptive processes [PDF]
Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis ...
Korolev, Kirill S. +2 more
core +2 more sources
Radiotherapy treatment of the common Keira's erythroplasia form
Bowen's disease, Keira's erythroplasia and bowenoid papulosis are currently classified as precancerous penis lesions associated with human papillomavirus (HPV). The diagnosis and treatment of precancerous penis lesions is a unique challenge.
F. R. Dzhabarov +2 more
doaj +1 more source
BCL-W has a fundamental role in B cell survival and lymphomagenesis. [PDF]
Compromised apoptotic signaling is a prerequisite for tumorigenesis. The design of effective therapies for cancer treatment depends on a comprehensive understanding of the mechanisms that govern cell survival.
Annette S. Kim +14 more
core +2 more sources
Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats [PDF]
Recent epidemiological studies suggest that high meat intake is associated with promotion of colon cancer linked to haem-iron intake. We previously reported that dietary haem, in the form of either haemoglobin or meat, promotes precancerous lesions in ...
Guéraud, Françoise +5 more
core +1 more source
Precancerous conditions increase the risk of gastric cancer by 2–3 % every 10 years. Among comorbid pathology, 46 % of all endocrinopathies are diseases of the thyroid gland.
Yu. M. Stepanov +6 more
doaj +1 more source
Serum Iron and Haemoglobin Estimation in Oral Submucous Fibrosis and Iron Deficiency Anaemia: A Diagnostic Approach [PDF]
Introduction: Oral Submucous Fibrosis (OSMF) is a premalignant condition with potential malignant behaviour characterized by juxta-epithelial fibrosis of the oral cavity.
Divya Bhardwaj +3 more
doaj +1 more source
Formate Excretion in Urine of Rats Fed Dimethylaminoazobenzene-rich Diets: The Possibility of Formate Formation from D-Lactate [PDF]
This experiment was carried out to evaluate the possibility of degradation of d-lactate into formate and acetaldehyde. In order to induce hyperproduction of d-lactate in rats.
Kawase, Michi +2 more
core +1 more source
Effect of probiotics on the development of dimethylhydrazine-induced preneoplastic lesions in the mice colon [PDF]
PURPOSE: To determine the effect of probiotics on the development of chemically induced (1, 2-dimethylhydrazine) colonic preneoplastic lesions, in mice. METHODS: The animals were divided into five groups.
Juliana Costa Liboredo +6 more
doaj +3 more sources
Efficacy of Oil Pulling in the Management of Oral Submucous Fibrosis: A Preliminary Study
Objective: To evaluate the effectiveness of oil pulling in the management of oral submucous fibrosis (OSMF). Material and Methods: A total of 62 patients clinically and histopathologically diagnosed as OSMF were incorporated in the present study.
Swatantra Shrivastava +6 more
doaj
Vaccines in Current Culture: The HPV Vaccine Controversy [PDF]
The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care.
Johnston, Alyssa
core +1 more source

