Results 51 to 60 of about 11,921 (298)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Synchronized sweep algorithms for scalable scheduling constraints [PDF]

open access: yes, 2013
This report introduces a family of synchronized sweep based filtering algorithms for handling scheduling problems involving resource and precedence constraints. The key idea is to filter all constraints of a scheduling problem in a synchronized way in
Letort, Arnaud   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Special Issue on Exact and Heuristic Scheduling Algorithms

open access: yesAlgorithms, 2019
This special issue of Algorithms is a follow-up issue of an earlier one, entitled ‘Algorithms for Scheduling Problems’. In particular, the new issue is devoted to the development of exact and heuristic scheduling algorithms.
Frank Werner   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Randomized and Generated Instances Fitting with the Home Health Care Problem Subjected to Certain Constraints

open access: yesApplied Sciences, 2021
Home Health Care (HHC) is a worldwide issue. It focuses on how medical and social organizations of different countries handle providing patients with health support at home. In most developed countries, reducing hospital cost constitutes a main objective.
Colin Huvent   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

An Asymptotic Cyclicity Analysis of Live Autonomous Timed Event Graphs

open access: yesApplied Sciences, 2021
Designing a discrete event system converging to steady temporal patterns is an essential issue of a system with time window constraints. Until now, to analyze asymptotic stability, we have modeled a timed event graph’s dynamic behavior, transformed it ...
Ja-Hee Kim
doaj   +1 more source

Stochastic Machine Scheduling with Precedence Constraints [PDF]

open access: yesSIAM Journal on Computing, 2005
We consider parallel, identical machine scheduling problems where the jobs are subject to precedence constraints, release dates, and the processing times of jobs are governed by independent probability distributions. The objective is to minimize the expected value of the total weighted completion time `&; w_j C_j, where w_jgeq 0`.
Skutella Martin, Uetz Marc
openaire   +5 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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