Results 61 to 70 of about 9,400 (263)
On the Approximability of Single-Machine Scheduling with Precedence Constraints [PDF]
Mathematics of Operations Research, 2011 We consider the single-machine scheduling problem to minimize the weighted sum of completion times under precedence constraints. In a series of recent papers, it was established that this scheduling problem is a special case of minimum weighted vertex cover.
Christoph Ambühl +3 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Locating service centers with precedence constraints
Discrete Applied Mathematics, 1993 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Y. Kaufman, Arie Tamir
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INCREMENTAL FILTERING ALGORITHMS FOR PRECEDENCE AND DEPENDENCY CONSTRAINTS [PDF]
International Journal on Artificial Intelligence Tools, 2006 Precedence constraints specify that an activity must finish before another activity starts and hence such constraints play a crucial role in planning and scheduling problems. Many real-life problems also include dependency constraints expressing logical relations between the activities – for example, an activity requires presence of another activity ...
Roman Barták, Ondrej Cepek
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Algorithms, 2019 Home Healthcare (HHC) is an emerging and fast-expanding service sector that gives rise to challenging vehicle routing and scheduling problems. Each day, HHC structures must schedule the visits of caregivers to patients requiring specific medical and ...
Syrine Roufaida Ait Haddadene +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source