Results 61 to 70 of about 11,921 (298)

Optimization of the Storage Location Assignment and the Picker-Routing Problem by Using Mathematical Programming

open access: yesApplied Sciences, 2020
The order picking process involves a series of activities in response to customer needs, such as the selection or programming of orders (batches), and the selection of different items from their storage location to shipment.
Johanna Bolaños Zuñiga   +3 more
doaj   +1 more source

Service Flow Management with deadline and budget Constraints using Genetic Algorithm in Heterogeneous Computing [PDF]

open access: yesIJCI International Journal of Computers and Information, 2019
The service flow management is one from the most challenges especially in heterogeneous environments which has several and various processors for computing. Service flow is used to explain services configuration process when service’s formation according
Ahmed AbdelHamed   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An Improved Approximation Algorithm for Scheduling Under Arborescence Precedence Constraints [PDF]

open access: yes, 2020
We consider a scheduling problem on unrelated machines with precedence constraints. There are m unrelated machines and n jobs and every job has to be processed non-preemptively in some machine.
Nguyen, Kim Thang, Thắng, Nguyễn Kim
core   +1 more source

Integrated multi-objective process planning and flexible job shop scheduling considering precedence constraints

open access: yesProduction and Manufacturing Research: An Open Access Journal, 2018
Process planning and scheduling decisions are independently performed in a manufacturing system in traditional approaches. Integration of these two decisions provides significant benefits such as enhancing the productivity of manufacturing resources ...
Elahe Shokouhi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A monotone approximation algorithm for scheduling with precedence constraints [PDF]

open access: yesOperations Research Letters, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sven Oliver Krumke   +3 more
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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