Results 81 to 90 of about 9,400 (263)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A Constraint Programming approach to solve the clustering problem in open-pit mine planning [PDF]

REM: International Engineering Journal
Since the open-pit precedence-constrained production scheduling problem is an NP-hard problem, solving it is always a challenging task, especially from a long-term perspective because a mineral deposit containing millions of blocks would require several ...
Jorge Luiz Valença Mariz, Rodrigo de Lemos Peroni, Ricardo Martins de Abreu Silva   +2 more
doaj   +1 more source

A Hybrid Grey Wolf Optimizer for Process Planning Optimization with Precedence Constraints. [PDF]

Materials (Basel), 2021
Milosevic M, Cep R, Cepova L, Lukic D, Antic A, Djurdjev M.   +5 more
europepmc   +1 more source

Improved Approximations for TSP with Simple Precedence Constraints [PDF]

, 2010
Technical report ...
Böckenhauer, Hans-Joachim, Klasing, Ralf, Mömke, Tobias, Steinová, Monika   +3 more
openaire   +5 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Ramping up a heuristic procedure for storage location assignment problem with precedence constraints. [PDF]

Flex Serv Manuf J, 2022
Trindade MAM, Sousa PSA, Moreira MRA.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

HLSA – A New Hybrid List Scheduling Algorithm for Fog Computing

Cybernetics and Information Technologies
A hybrid list scheduling algorithm is applied in fog computing with heterogeneity in available resources and incoming scheduling units. The scheduling units that need to be scheduled can be independent with no precedence constraints, so that tasks can be
Ali Hend Gamal El Din Hassan, Saroit Imane Aly, Kotb Amira Mohamed   +2 more
doaj   +1 more source

QUBO Formulations and Quantum Optimization for the Multi-Dimensional Knapsack Problem With Conflict, Forcing, and Precedence Constraints

IEEE Access
Constrained knapsack variants are well-suited for QUBO-based quantum optimization, but adding logical relations can inflate the binary model and complicate penalty selection.
Evren Guney, Joachim Ehrenthal
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source