Results 51 to 60 of about 763,867 (328)

Keep Ballots Secret: On the Futility of Social Learning in Decision Making by Voting [PDF]

open access: yes, 2012
We show that social learning is not useful in a model of team binary decision making by voting, where each vote carries equal weight. Specifically, we consider Bayesian binary hypothesis testing where agents have any conditionally-independent observation
Goyal, Vivek K., Rhim, Joong Bum
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

On Precedents in General and in a Statutory Legal System

open access: yesStudia Iuridica Lublinensia, 2018
The article touches upon the issue of precedent (in both the codified law and common law systems) as a source of law. The author presents concepts of the law philosophers, often contradictory to one another, which refer to the understanding of the very ...
Alexander Bröstl
doaj   +1 more source

A terminal molybdenum carbide prepared by methylidyne deprotonation [PDF]

open access: yes, 1997
The carbide anion [CMo{N(R)Ar}_3]– [R = C(CD_3)_2CH_3, Ar = C_6H_3Me_2-3,5], is obtained by deprotonation of the corresponding methylidyne compound, [HCMo{N(R)Ar}_3], and is characterized by X-ray diffraction as its {K(benzo-15-crown-5)_2}+ salt, thereby
Cummins, Christopher C.   +2 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Precedent as an Element of Shaping Public Administration Policies

open access: yesStudia Iuridica Lublinensia, 2018
The aim of this publication is to answer the question why and to what extent the arguments expressed in previous decisions issued in the result of law application processes (precedents) – both from the administration itself as well as from the judiciary –
Adam Szot
doaj   +1 more source

Originalist Theory and Precedent: A Public Meaning Approach [PDF]

open access: yes, 2018
Much ink has already been spilled on the relationship of constitutional originalism to precedent (or, more specifically, the doctrine of stare decisis). The debate includes contributions from Randy Barnett, Steven Calabresi, Kurt Lash, Gary Lawson, John ...
Solum, Lawrence B.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The gem hidden behind Predictability: Discussing efficiency in and of Investment arbitration [PDF]

open access: yesPravni Zapisi
The paper discusses the status quo regarding efficiency in investment arbitration and suggests how predictability of the arbitral outcome can improve both efficiency in and of investment arbitration. First, the paper will address the cost and duration of
Rajković Nataša
doaj   +1 more source

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