Results 91 to 100 of about 1,356,070 (297)

Computation Precedes Naming: Naming Returns Computation

open access: yes
  Structural nonclosure on the classical computation carrier (binary strings with drop/prepend). Three independent  machine-checked proofs that the section does not close: no structure-preserving map from the frictionless model  (fold_unfold_nonclosure, six lines, omega); selfApp not equal to identity (presemantic_not_group_C); irreducible  factoring ...
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Precedent name «Kain» in the modern German-speaking journalistic discourse

open access: yes, 2018
Стаття присвячена проблематиці прецедентних імен як важливої частини німецької лінгвокультури. Біблійний епізод братовбивства описаний з точки зору теорії реплікації.
Гаврилова, И. Н.
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Meaning-Making Processes in Derivatives from Precedent Names

open access: yes, 2016
The paper addresses the issue of meaning-making in a highly prolific and sprawling segment of English vocabulary – derivatives from precedent names (DPNs).
Ekaterina Golubkova, Anastasia Zakharova
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Overruling and the Instability of Law [PDF]

open access: yes
We investigate the evolution of common law under overruling, a system of precedent change in which appellate courts replace existing legal rules with new ones.
Andrei Shleifer, Nicola Gennaioli
core  

Precedent, Super-Precedent [PDF]

open access: yes, 2006
The idea of super-precedent was first posited by (then) Prof. Posner & Prof. Landis 30 years ago, but as a throw-away, and was not picked up in the jargon.
Sinclair, Michael B.W.   +1 more
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

THE NAME OF LUDWIG VAN BEETHOVEN AS THE PRECEDENT LEXICAL ITEM IN ANTHONY BURGESS’S NOVEL “A CLOCKWORK ORANGE”

open access: yesВестник Кемеровского государственного университета, 2017
The article analyzes features of the proper name of Ludwig van Beethoven as well as represents its intentional use in the process of verbalization of the phenomenon “Music” (based on the novel “A Clockwork” by Orange A. Burgess).
L. V. Korobko
doaj   +1 more source

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