Results 71 to 80 of about 59,674 (293)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Judicial precedents study

open access: yesJournal of Human Environmental Studies, 2008
This essay is to interpret and to add some comments for the Legal Case of Repeal Request (Judgment of the Supreme Court on Oct. 09. 2007). On this case, Plaintiff, the students over 20years old, who go disabled persons, insisted that the National Pension
Satomi Kohyama
doaj   +1 more source

Practical Conveyancing Precedents [Release 47]

open access: yes, 2015
A comprehensive collection of conveyancing forms for use in every conceivable situation, Practical Conveyancing Precedents: - Contains complete contracts plus hundreds of precedent clauses enabling you to prepare conveyancing documents for virtually ...
Alridge, Trevor   +2 more
core  

Segundo Torrão: Marginality seen in urban policy and the historical precedents of territorial fixation and stigmatization

open access: yes, 2020
Segundo Torrão: Marginality seen in urban policy and the historical precedents of territorial fixation and stigmatization – Loukia Batsi The present work follows the connections between the marginality seen in urban policy and the historical ...
Loukia Batsi
core  

Precedents in Constitutional Courts

open access: yes, 2021
The presentation delivers some thought on interim results of research on precedents in constitutional courts over the ...
Belov, Sergei
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

FROM JUDICIAL PRECEDENTS TO BINDING PRECEDENTS: ADVANTAGES OR THREATS TO LOWER COURTS?

open access: yesRevista Eletrônica de Direito Processual, 2018
The theories of legal argumentation, globalization in the legal field and the consolidation of constitutional jurisdictions have promoted the progressive centrality of jurisprudence in our days, thanks to the leading role recognized in the judicial ...
Nuria Belloso Martín
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy