Results 91 to 100 of about 163,476 (344)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

FROM JUDICIAL PRECEDENTS TO BINDING PRECEDENTS: ADVANTAGES OR THREATS TO LOWER COURTS?

open access: yesRevista Eletrônica de Direito Processual, 2018
The theories of legal argumentation, globalization in the legal field and the consolidation of constitutional jurisdictions have promoted the progressive centrality of jurisprudence in our days, thanks to the leading role recognized in the judicial ...
Nuria Belloso Martín
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Estate planning precedents ::a solicitor's manual.

open access: yes, 2020
Text of Histrop's estate planning precedents, by Lindsay Ann Histrop, which includes a wide variety of precedents covering all aspects of wills and ...
Histrop, Lindsay Ann,   +1 more
core  

Precedence Automata and Languages [PDF]

open access: yes, 2011
Extended version of the paper which appeared in Proceedings of CSR 2011, Lecture Notes in Computer Science, vol. 6651, pp. 291-304, 2011.
V. Lonati   +2 more
openaire   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Adaptive management of an enterprise on the basis of precedents: agent specific approach Адаптивное управление предприятиями на основе прецедентов: агентно-ориентированный подход [PDF]

open access: yesProblemi Ekonomiki, 2013
Organisational and economic stability of economic objects in market conditions depends, first of all, on what principles the relevant system of management is based and functioning. It is evident that such a system should be adaptive.
Guzhva Vladimir M.
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The evolution of health warning labels on cigarette packs: the role of precedents, and tobacco industry strategies to block diffusion

open access: yesTobacco Control, 2012
Objective To analyse the evolution and diffusion of health warnings on cigarette packs around the world, including tobacco industry attempts to block this diffusion.
H. Hiilamo, E. Crosbie, S. Glantz
semanticscholar   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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