Results 41 to 50 of about 1,540,346 (240)

Optimal Ranking Regime Analysis of Intra- to Multidecadal U.S. Climate Variability. Part II: Precipitation and Streamflow [PDF]

, 2014
In Part I of this paper, the optimal ranking regime (ORR) method was used to identify intradecadal to multidecadal (IMD) regimes in U.S. climate division temperature data during 1896–2012.
Cordero, Eugene C., Mauget, Steven A.
core   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

European precipitation connections with large-scale mean sea-level pressure (MSLP) fields [PDF]

, 2013
To advance understanding of hydroclimatological processes, this paper links spatiotemporal variability in gridded European precipitation and large-scale mean sea-level pressure (MSLP) time series (1957–2002) using monthly concurrent correlation.
Hannah, David M., Lavers, David, Prudhomme, Christel   +2 more
core   +2 more sources

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

The transient response of global-mean precipitation to increasing carbon dioxide levels [PDF]

, 2010
The transient response of global-mean precipitation to an increase in atmospheric carbon dioxide levels of 1% yr(-1) is investigated in 13 fully coupled atmosphere-ocean general circulation models (AOGCMs) and compared to a period of stabilization ...
Bala G, Meehl G A, Mitchell J F B, Piers M Forster, Timothy Andrews, Wild M   +5 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Trends of precipitation extreme indices over a subtropical semi-arid area using PERSIANN-CDR [PDF]

, 2016
In this study, satellite-based daily precipitation estimation data from precipitation estimation from remotely sensed information using artificial neural networks (PERSIANN)-climate data record (CDR) are being evaluated in Iran.
Ashouri, H, Hsu, KL, Katiraie-Boroujerdy, PS, Sorooshian, S   +3 more
core   +1 more source

Precipitate Labor [PDF]

The American Journal of the Medical Sciences, 1906
n ...
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Climate Dynamics: A Network-Based Approach for the Analysis of Global Precipitation [PDF]

, 2013
Precipitation is one of the most important meteorological variables for defining the climate dynamics, but the spatial patterns of precipitation have not been fully investigated yet. The complex network theory, which provides a robust tool to investigate
A Becker, A Gozolchiani, A Kolzsch, AA Tsonis, AA Tsonis, AA Tsonis, AJ Simmons, Alex J. Cannon, AS Cofiño, B Rajagopalan, C Chou, D Hemming, DJ Watts, DL Montroy, DR Archer, F Raicich, Francesco Laio, GJ McCabe, GJ van Oldenborgh, J Heitzig, J Kennedy, J Kennedy, J Kennedy, J Shaman, JE Hansen, JF Diaz, JF Donges, JF Donges, JF Donges, JM Ryoo, JP Boulanger, JW Hurrell, K Steinhaeuser, K Yamasaki, KF Davis, LC Freeman, LD Costa, LD Costa, LL Chen, Luca Ridolfi, M Fritsche, M Palus, MEJ Newman, N Malik, R Albert, R Cano, RH Kripalani, S Abe, S Boccaletti, S Brönnimann, S Fatichi, S Michaelides, S Saeed, SE Nicholson, Stefania Scarsoglio, T Zhou, U Gessner, U Schneider, V Petoukhova, W Chen   +59 more
core   +4 more sources