Results 101 to 110 of about 440,435 (279)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Galileo-based precise point positioning with different MGEX products

open access: yesMeasurement Science and Technology, 2020
Considering the remarkable progress of the Galileo constellation in recent years, the main objective of this study is to evaluate the performance of dual- and single-frequency Galileo-based precise point positioning (PPP), and its contribution to GPS and Galileo integration with different precise products generated by four analysis centers (ACs) within
Berkay Bahadur, Metin Nohutcu
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

SHAtropE—A Regional Gridded ZTD Model for China and the Surrounding Areas

open access: yesRemote Sensing, 2020
A regional zenith tropospheric delay (ZTD) empirical model, referred to as SHAtropE (SHanghai Astronomical observatory tropospheric delay model—Extended), is developed and provides tropospheric propagation delay corrections for users in China and ...
Junping Chen   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Integrated real-time precise point positioning system with B2b/B2a/B1C services

open access: yesSatellite Navigation
Real-Time Precise Point Positioning (RTPPP) technology is one of the most important means of positioning and navigation, whereas this type of service requires Internet access.
Zhetao Zhang, Hao Wang, Yuanxi Yang
doaj   +1 more source

A Decentralized Processing Schema for Efficient and Robust Real-time Multi-GNSS Satellite Clock Estimation

open access: yesRemote Sensing, 2019
Real-time multi-GNSS precise point positioning (PPP) requires the support of high-rate satellite clock corrections. Due to the large number of ambiguity parameters, it is difficult to update clocks at high frequency in real-time for a large reference ...
Xinyuan Jiang   +4 more
doaj   +1 more source

Hybrid Urban Navigation for Smart Cities

open access: yes, 2017
This paper proposes a design for a hybrid, city-wide urban navigation system for moving agents demanding dedicated assistance. The hybrid system combines GPS and vehicle-to-vehicle communication from an ad-hoc network of parked cars, and RFID from fixed ...
Gilmore, Robert   +3 more
core   +1 more source

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