Results 101 to 110 of about 5,818,450 (268)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Investigation of the effects of specific solar storming events on GNSS navigation systems / Charakteringų saulės audrų poveikio globalinei navigacinei palydovinei sistemai tyrimas

open access: yesAviation, 2011
Global positioning system (GPS) satellites operate at 1.2 and 1.5 GHz. The GPS signals travel through the atmosphere and are affected by space weather in the same way as other technological systems in space and on the ground.
Vilma Zubinaitė, George Preiss
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Integrated real-time precise point positioning system with B2b/B2a/B1C services

open access: yesSatellite Navigation
Real-Time Precise Point Positioning (RTPPP) technology is one of the most important means of positioning and navigation, whereas this type of service requires Internet access.
Zhetao Zhang, Hao Wang, Yuanxi Yang
doaj   +1 more source

Multi-GNSS precise point positioning with next-generation smartphone measurements

open access: yes, 2019
This study evaluates the feasibility of achieving improved positioning accuracy with raw GNSS measurements from recently released smartphones. Using Precise Point Positioning (PPP) as the processing mode, positioning accuracy of selected newly available ...
Sunil Bisnath (7459772)   +4 more
core   +1 more source

Performance Evaluation of Real-Time Precise Point Positioning Method [PDF]

open access: yes, 2017
3rd World Multidisciplinary Earth Sciences Symposium (WMESS) -- SEP 11-15, 2017 -- Prague, CZECH REPUBLICPost-Processed Precise Point Positioning (PPP) is a well-known zero-difference positioning method which provides accurate and precise results.
Salih Alcay   +3 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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