Results 121 to 130 of about 101,629 (318)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Fast Precise Point Positioning based on real-time ionospheric modelling
Summary of main results of new technique Fast Precise Point Positioning developed in the framework of the “Enhanced Precise Point Positioning (EPPP) GNSS multifrequency user algorithm” ESA funded project.
Samson, Jaron +4 more
core +1 more source
Comparison and assessment of float, fixed, and smoothed precise point positioning [PDF]
Pavel Václavovic
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Ionospheric delay as the major error source needs to be properly handled in multi-GNSS (Global Navigation Satellite System) single-frequency positioning and the different ionospheric models exhibit apparent performance difference.
Ahao Wang +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Position Dilution of Precision: a Bayesian point of view
The expected position error in many cases is far from feasible to be estimated experimentally using real satellite measurements which makes the model-based position dilution of precision (PDOP) crucial in positioning and navigation applications. In the following text we derive the relationship between PDOP and position error and we explain that this ...
Koulouri, Alexandra +2 more
openaire +2 more sources
Assessment of Single and Precise Point Positioning Over Long Observational Periods [PDF]
Mohamed El‐Tokhey
openalex +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

