Results 151 to 160 of about 850,443 (319)

Tightly coupled precise point positioning and attitude determination [PDF]

open access: yesIEEE Transactions on Aerospace and Electronic Systems, 2015
A method is described for joint precise point positioning and attitude determination with tight coupling of two single-frequency low-cost global navigation satellite system receivers and an inertial sensor. The sensor fusion is performed with an extended Kalman filter. The carrier phase ambiguities are determined in a constrained tree search using soft
openaire   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Note on improvement precision of recursive function simulation in floating point standard [PDF]

open access: yesarXiv, 2017
An improvement on precision of recursive function simulation in IEEE floating point standard is presented. It is shown that the average of rounding towards negative infinite and rounding towards positive infinite yields a better result than the usual standard rounding to the nearest in the simulation of recursive functions.
arxiv  

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Precise Point Positioning Augmentation for Various Grades of Global Navigation Satellite System Hardware [PDF]

open access: yes, 2020
The next generation of low-cost, dual-frequency, multi-constellation GNSS receivers, boards, chips and antennas are now quickly entering the market, offering to disrupt portions of the precise GNSS positioning industry with much lower cost hardware and ...
Aggrey, John Egyir
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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