Results 111 to 120 of about 1,922,046 (318)

Prevention, precision prevention and precision medicine

open access: yesExposome
Abstract It has been proposed that the measurement of the sequence of exposures an individual is exposed to over time (or “expotype,” complementary to the genotype) would be a way to promote precision medicine at the patient’s bed, and also primary prevention.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

RISK MANAGEMENT POTENTIAL OF PRECISION FARMING TECHNOLOGIES

open access: yes
Initial ideas on risk management uses of precision agricultural technology focused on site-specific treatment of problem areas to reduce the probability of low yields and returns.
Lowenberg-DeBoer, James
core  

[Franklin Mint Precision Motors model car advert]

open access: yes, 1987
A pamphlet displaying Franklin Mint Precision replica vehicle ...
Franklin Mint Precision Motors
core  

Validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article describes validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy. The procedure makes it possible to determine the molar ratio of amino acids present in glatiramer acetate with ...
N. E. Kuz’Mina   +6 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

[Franklin Mint Precision Models Owner's manual]

open access: yes, 1987
Owner's manual for Franklin Mint Precision ...
Franklin Mint Precision Motors
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Precision machine tools

open access: yes, 2022
S.519-523Conventional cutting processes are highly qualified for the manufacturing of micro and precision parts. The paper describes the various parameters which have influence on the work piece quality and gives a review of different machine tools ...
Weck, Manfred   +2 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

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